Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230699 | 0.79 | PKM (0.42) | GRM5PKMLMNA | |
| SCHEMBL19230555 | 0.76 | GRM5 (0.42) | GRM5MRGPRX4PKMPDE5A | |
| SCHEMBL19230819 | 0.75 | GRM5 (0.42) | GRM5MRGPRX4PKM | |
| SCHEMBL19230697 | 0.73 | KDM4E (0.51) | — | |
| SCHEMBL695145 | 0.71 | AR (0.52) | MRGPRX4LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL2524154 | 0.70 | L3MBTL1 (0.52) | GRM5TRPV3PKMLMNACYP1A2 | |
| SCHEMBL29013224 | 0.70 | SQOR (0.39) | GRM5PDE5A | |
| SCHEMBL7840899 | 0.69 | TRPV3 (0.59) | GRM5TRPV3PKMLMNACYP1A2 | |
| SCHEMBL8429140 | 0.68 | MRGPRX4 (0.67) | MRGPRX4 | |
| SCHEMBL26043730 | 0.68 | L3MBTL1 (0.45) | GRM5TRPV3PKMPDE5ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602811-B | FXR receptor agonists | 轩竹生物科技有限公司 | 2021-11-16 | — | — | CN | disclosed |
| CN-108602811-A | FXR receptor stimulating agents | 山东轩竹医药科技有限公司 | 2018-09-28 | — | — | CN | disclosed |
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |