Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.60 |
| ▸ | CTSD | P07339 | 16/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25916086 | 0.75 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL2910973 | 0.60 | BACE1 (0.43) | BACE1CTSD | |
| SCHEMBL29560345 | 0.57 | ALOX15 (0.66) | — | |
| SCHEMBL376840 | 0.57 | ALOX15 (0.66) | — | |
| SCHEMBL506396 | 0.56 | ACHE (0.43) | BACE1 | |
| SCHEMBL16302768 | 0.56 | CA1 (0.52) | BACE1CTSD | |
| SCHEMBL16378743 | 0.55 | GRIN2B (0.65) | — | |
| SCHEMBL2906765 | 0.55 | MIF (0.49) | BACE1 | |
| SCHEMBL13649201 | 0.55 | THRA (0.38) | BACE1CTSD | |
| SCHEMBL1438878 | 0.55 | TRPA1 (0.64) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133517-A1 | PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF | 四川海思科制药有限公司 | 2017-08-10 | — | — | WO | disclosed |