Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 17/20 | 0.82 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535908 | 0.91 | KCNH3 (1.00) | KCNH3 | |
| SCHEMBL1280999 | 0.85 | KCNH3 (1.00) | KCNH3 | |
| SCHEMBL1923769 | 0.85 | KCNH3 (0.67) | KCNH3RECQLMCL1 | |
| SCHEMBL1923808 | 0.83 | MAOA (0.69) | KCNH3RECQLMCL1 | |
| SCHEMBL11281985 | 0.81 | MAOA (0.64) | KCNH3MAPTKMT2AKDM4E | |
| SCHEMBL540957 | 0.79 | KCNH3 (0.86) | KCNH3MAPK1KDM4E | |
| SCHEMBL633400 | 0.78 | MEN1 (0.77) | KCNH3RECQLMCL1MEN1MAPT | |
| SCHEMBL1924273 | 0.77 | KCNH3 (1.00) | KCNH3RECQLMCL1 | |
| SCHEMBL1282182 | 0.76 | KCNH3 (1.00) | KCNH3MEN1MAPTKMT2AMAPK1 | |
| SCHEMBL15102583 | 0.76 | MAOA (0.58) | KCNH3RECQLMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1479397-B1 | 2,4,6-TRIAMINO-1,3,5-TRIAZINE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2011-06-08 | — | — | EP | claimed |
| US-7375222-B2 | 2,4,6-Triamino-1,3,5-triazine derivative | ASTELLAS PHARMA INC. (JP) | 2008-05-20 | — | — | US | claimed |