Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1280999 | 0.95 | KCNH3 (1.00) | KCNH3 | |
| SCHEMBL1923771 | 0.91 | KCNH3 (0.82) | KCNH3 | |
| SCHEMBL540957 | 0.89 | KCNH3 (0.86) | KCNH3 | |
| SCHEMBL1282182 | 0.85 | KCNH3 (1.00) | KCNH3 | |
| SCHEMBL1924158 | 0.82 | KCNH3 (0.71) | KCNH3 | |
| SCHEMBL1923791 | 0.81 | KCNH3 (0.97) | KCNH3 | |
| SCHEMBL1923769 | 0.80 | KCNH3 (0.67) | KCNH3 | |
| SCHEMBL1923864 | 0.80 | KCNH3 (0.90) | KCNH3 | |
| SCHEMBL1281719 | 0.80 | KCNH3 (0.97) | KCNH3 | |
| SCHEMBL5015069 | 0.80 | KCNH3 (0.66) | KCNH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1479397-B1 | 2,4,6-TRIAMINO-1,3,5-TRIAZINE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2011-06-08 | — | — | EP | claimed |
| US-7375222-B2 | 2,4,6-Triamino-1,3,5-triazine derivative | ASTELLAS PHARMA INC. (JP) | 2008-05-20 | — | — | US | claimed |
| US-8399663-B2 | Salt of 1,3,5-triazine-2,4,6-triamine derivative | ASTELLAS PHARMA INC. (JP) | 2013-03-19 | — | — | US | disclosed |
| US-8399663-B2 | Salt of 1,3,5-triazine-2,4,6-triamine derivative | ASTELLAS PHARMA INC. (JP) | 2013-03-19 | — | — | US | disclosed |
| US-8399663-B2 | Salt of 1,3,5-triazine-2,4,6-triamine derivative | ASTELLAS PHARMA INC. (JP) | 2013-03-19 | — | — | US | disclosed |
| US-8399663-B2 | Salt of 1,3,5-triazine-2,4,6-triamine derivative | ASTELLAS PHARMA INC. (JP) | 2013-03-19 | — | — | US | disclosed |
| US-20120088772-A1 | NOVEL PHARMACEUTICAL COMPOSITION FOR PREVENTION AND/OR TREATMENT OF ATTENTION DEFICIT/HYPERACTIVITY DISORDER | ASTELLAS PHARMA INC. (JP) | 2012-04-12 | — | — | US | disclosed |
| EP-2414351-A1 | NOVEL SALT OF 1,3,5-TRIAZINE-2,4,6-TRIAMINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2012-02-08 | — | — | EP | disclosed |
| EP-2413940-A1 | COMPOSITIONS COMPRISING 2, 4, 6-TRIAMINO-1, 3, 5-TRIAZINE DERIVATIVES FOR TREATMENT OF SCHIZOPHRENIA | Astellas Pharma Inc. (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20100256151-A1 | NOVEL SALT OF 1,3,5-TRIAZINE-2,4,6-TRIAMINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
| US-20100256151-A1 | NOVEL SALT OF 1,3,5-TRIAZINE-2,4,6-TRIAMINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
| US-20100256151-A1 | NOVEL SALT OF 1,3,5-TRIAZINE-2,4,6-TRIAMINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
| US-20100256151-A1 | NOVEL SALT OF 1,3,5-TRIAZINE-2,4,6-TRIAMINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
| WO-2010114163-A1 | COMPOSITIONS COMPRISING 2, 4, 6-TRIAMINO-1, 3, 5-TRIAZINE DERIVATIVES FOR TREATMENT OF SCHIZOPHRENIA | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | WO | disclosed |
| WO-2010114162-A1 | NOVEL SALT OF 1,3,5-TRIAZINE-2,4,6-TRIAMINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | WO | disclosed |
| US-20100256152-A1 | NOVEL PHARMACEUTICAL COMPOSITION FOR TREATMENT OF SCHIZOPHRENIA | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
| WO-2010114162-A1 | NOVEL SALT OF 1,3,5-TRIAZINE-2,4,6-TRIAMINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256152-A1 | NOVEL PHARMACEUTICAL COMPOSITION FOR TREATMENT OF SCHIZOPHRENIA | KCNAB1, KCNN1, SCN1A | KCNH3 81/4885 |
| US-20120088772-A1 | NOVEL PHARMACEUTICAL COMPOSITION FOR PREVENTION AND/OR TREATMENT OF ATTENTION DEFICIT/HYPERACTIVITY DISORDER | SLC6A3, ATP1A2, SLC6A1 | KCNH3 105/4885 |
| US-20100256151-A1 | NOVEL SALT OF 1,3,5-TRIAZINE-2,4,6-TRIAMINE DERIVATIVE | FH, FAH, GOT1 | KCNH3 2436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.