SCHEMBL19239063

SCHEMBL19239063

c1ccc(-c2cccc(N(c3ccc4c(c3)sc3ccccc34)c3ccc4sc5cc(N(c6ccccc6)c6ccccc6)ccc5c4c3)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.41
ALDH1A1 P00352 3/20 0.41
HPGD P15428 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
GPR3 P46089 1/20 0.39
CYP1A2 P05177 2/20 0.35
LIMK1 P53667 2/20 0.34
PTPN7 P35236 1/20 0.34
DUSP3 P51452 1/20 0.34
PTPN12 Q05209 1/20 0.34
PTPN22 Q9Y2R2 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
F9 P00740 2/20 0.33
APP P05067 1/20 0.33
TNKS O95271 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
POLB P06746 1/20 0.33
PIM3 Q86V86 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19239065 1.00 MAPT (0.41) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL23172167 1.00 MAPT (0.41) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL19429319 1.00 MAPT (0.41) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL19429073 0.99 ALDH1A1 (0.40) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL19429071 0.99 ALDH1A1 (0.40) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL19429014 0.99 MAPT (0.41) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL21966491 0.97 ALDH1A1 (0.36) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL19596665 0.96 ALDH1A1 (0.40) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL21242396 0.96 MAPT (0.40) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL19429039 0.96 LIMK1 (0.37) MAPTALDH1A1HPGDRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210098706-A1 ORGANIC ELECTRIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRIC ELEMENT AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2021-04-01 US disclosed
US-10319915-B2 Compound for organic electronic element, organic electronic element using the same, and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2019-06-11 US disclosed
US-20180151806-A2 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-05-31 US disclosed
US-20180151806-A2 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-05-31 US disclosed
US-20170237013-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2017-08-17 US disclosed
US-20170237013-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2017-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210098706-A1 ORGANIC ELECTRIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRIC ELEMENT AND ELECTRONIC DEVICE THEREOF EED, PIEZO1, TRPA1 MAPT 655/4885ALDH1A1 1943/4885HPGD 2996/4885
US-10319915-B2 Compound for organic electronic element, organic electronic element using the same, and an electronic device thereof EML4, EBPL, NFE2L2 MAPT 881/4885ALDH1A1 1021/4885HPGD 3558/4885
US-20170237013-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF EML4, EBPL, NFE2L2 MAPT 881/4885ALDH1A1 1021/4885HPGD 3558/4885
US-20180151806-A2 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF EBPL, EML4, NFE2L2 MAPT 975/4885ALDH1A1 919/4885HPGD 3851/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.