Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.37 |
| ▸ | MAOB | P27338 | 6/20 | 0.37 |
| ▸ | KDM1A | O60341 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19248980 | 0.74 | ADAM17 (0.44) | NPSR1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL11424700 | 0.72 | MAOA (0.44) | MAOAMAOBKDM1ANPSR1KMT2A | |
| SCHEMBL6256448 | 0.70 | CA2 (0.38) | MAOBNPSR1KMT2AMAPTL3MBTL1 | |
| SCHEMBL1062160 | 0.70 | CA2 (0.38) | MAOBNPSR1KMT2AMAPTL3MBTL1 | |
| SCHEMBL6810670 | 0.68 | ELANE (0.43) | MAOAMAOBNPSR1KMT2AELANE | |
| SCHEMBL19239808 | 0.65 | ELANE (0.40) | MAOAMAOBNPSR1KMT2AELANE | |
| SCHEMBL18805033 | 0.64 | ELANE (0.42) | MAOAMAOBNPSR1ELANEBACE1 | |
| SCHEMBL16435876 | 0.64 | KMT2A (0.39) | MAOAMAOBKDM1ANPSR1KMT2A | |
| SCHEMBL5065445 | 0.63 | MAOA (0.45) | MAOAMAOBKDM1AELANEOPRM1 | |
| SCHEMBL2525239 | 0.63 | MAOA (0.45) | MAOAMAOBKDM1AELANEOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170233405-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233405-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MYC, MYCBP, MYCBP2 | MAOA 2670/4885MAOB 1976/4885KDM1A 2170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.