Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 4/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1723830 | 0.81 | FFAR1 (0.59) | FFAR1LTA4HBCHEPPARGPPARA | |
| SCHEMBL8157173 | 0.74 | MMP12 (0.61) | FFAR1SIGMAR1LTA4HEPHX2BCHE | |
| SCHEMBL28176410 | 0.72 | LTA4H (0.65) | FFAR1SIGMAR1LTA4HEPHX2BCHE | |
| SCHEMBL25108838 | 0.71 | BCHE (0.57) | BCHE | |
| SCHEMBL10875504 | 0.70 | ALOX5 (0.57) | LTA4HBCHE | |
| SCHEMBL10877817 | 0.70 | ALOX5 (0.57) | LTA4HBCHE | |
| SCHEMBL27677483 | 0.70 | LTA4H (0.62) | FFAR1SIGMAR1LTA4HEPHX2BCHE | |
| SCHEMBL8149319 | 0.70 | ALOX5 (0.57) | FFAR1LTA4HEPHX2BCHE | |
| SCHEMBL23641504 | 0.70 | CYP17A1 (0.51) | FFAR1LTA4HPPARGPPARA | |
| SCHEMBL14118337 | 0.69 | BCHE (0.55) | FFAR1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170233414-A1 | DERIVATIVES OF BODIPY | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233414-A1 | DERIVATIVES OF BODIPY | NPC1L1, NPC1, ABCB4 | FFAR1 281/4885SIGMAR1 2791/4885LTA4H 2000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.