Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2526240 | 0.82 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL1419109 | 0.82 | — | — | |
| SCHEMBL992245 | 0.80 | ALDH1A1 (0.32) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Acetic Acid SCHEMBL20657787 | 0.73 | FFAR3 (0.39) | CHRM1TDP1ALDH1A1 | |
| SCHEMBL487333 | 0.70 | TDP1 (0.38) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL487120 | 0.70 | TDP1 (0.38) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL1262653 | 0.70 | TDP1 (0.38) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL9586717 | 0.70 | RNPEP (0.38) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL1952253 | 0.69 | — | — | |
| SCHEMBL249763 | 0.69 | MAPT (0.35) | CHRM1AKR1A1CHRM3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654661-A | Curable silicone composition and light diffusing material formed therefrom | 美国陶氏有机硅公司 | 2021-04-13 | — | — | CN | disclosed |
| EP-1504051-B1 | ORGANO-FUNCTIONAL POLYSILOXANES | SIGMAKALON SERVICES B V (NL) | 2011-06-08 | — | — | EP | disclosed |
| EP-1608694-B1 | PROCESS FOR THE PREPARATION OF HIGH SOLIDS URETHANE ALKYDS | PPG BV (NL) | 2008-11-05 | — | — | EP | disclosed |
| US-20060252953-A1 | Process for the production of silyl carboxylate monomers | SIGMA COATINGS B.V. (NL) | 2006-11-09 | — | — | US | disclosed |
| US-7118621-B2 | Organo-functional polysiloxanes | SIGMAKALON SERVICES B.V. (NL) | 2006-10-10 | — | — | US | disclosed |
| EP-0990660-B1 | PROCESS FOR PREPARING CYCLIC OLIGOSILOXANES | KANEKA CORP (JP) | 2006-04-26 | — | — | EP | disclosed |
| EP-1608694-A1 | PROCESS FOR THE PREPARATION OF HIGH SOLIDS URETHANE ALKYDS | SigmaKalon B.V. (NL) | 2005-12-28 | — | — | EP | disclosed |
| US-20050222446-A1 | Process for the production of hydrocarbyl silyl carboxylate compounds | SIGMA COATINGS B.V. (NL) | 2005-10-06 | — | — | US | disclosed |
| US-20050202257-A1 | Organo-functional polysiloxanes | SIGMAKALON SERVICES B.V. (NL) | 2005-09-15 | — | — | US | disclosed |
| EP-1572701-A1 | PROCESS FOR THE PRODUCTION OF HYDROCARBYL SILYL CARBOXYLATE COMPOUNDS | SIGMA COATINGS B.V. (NL) | 2005-09-14 | — | — | EP | disclosed |
| EP-1501884-A1 | AMINO-FUNCTIONAL POLYSILOXANES AND THEIR USE IN COATINGS | SigmaKalon Services B.V. (NL) | 2005-02-02 | — | — | EP | disclosed |
| WO-2004101639-A1 | PROCESS FOR THE PREPARATION OF HIGH SOLIDS URETHANE ALKYDS | SIGMAKALON B.V. (NL) | 2004-11-25 | — | — | WO | disclosed |
| WO-2004056837-A1 | PROCESS FOR THE PRODUCTION OF HYDROCARBYL SILYL CARBOXYLATE COMPOUNDS | SIGMA COATINGS B.V. (NL) | 2004-07-08 | — | — | WO | disclosed |
| EP-1431301-A1 | Process for the production of silyl carboxylate monomers | SIGMA COATINGS B.V. (NL) | 2004-06-23 | — | — | EP | disclosed |
| WO-2003093352-A1 | AMINO-FUNCTIONAL POLYSILOXANES AND THEIR USE IN COATINGS | SIGMAKALON SERVICES B.V. (NL) | 2003-11-13 | — | — | WO | disclosed |
| WO-2003093350-A1 | ORGANO-FUNCTIONAL POLYSILOXANES | SIGMAKALON SERVICES B.V. (NL) | 2003-11-13 | — | — | WO | disclosed |
| EP-1361245-A1 | Amino-functional polysiloxanes | SigmaKalon Group B.V. (NL) | 2003-11-12 | — | — | EP | disclosed |
| EP-1359182-A1 | Organo-functional polysiloxanes | SigmaKalon Group B.V. (NL) | 2003-11-05 | — | — | EP | disclosed |
| US-6262289-B1 | HEATING IN PRESENCE OF METAL ALKOXIDE | KANEKA CORPORATION (JP) | 2001-07-17 | — | — | US | disclosed |
| EP-0990660-A1 | PROCESS FOR PREPARING CYCLIC OLIGOSILOXANES | Kaneka Corporation (JP) | 2000-04-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252953-A1 | Process for the production of silyl carboxylate monomers | ACSL1, SUCLA2, MSMO1 | CHRM1 1171/4885AKR1A1 310/4885CHRM3 2300/4885 |
| US-20050222446-A1 | Process for the production of hydrocarbyl silyl carboxylate compounds | FTO, SUCLG2, ALKBH3 | CHRM1 1107/4885AKR1A1 685/4885CHRM3 1328/4885 |
| US-20050202257-A1 | Organo-functional polysiloxanes | H1-3, HAO2, LPO | CHRM1 141/4885AKR1A1 668/4885CHRM3 203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.