Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 6/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | ULK1 | O75385 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19256900 | 0.82 | SMYD3 (0.48) | SMYD3SMN1; SMN2KDM2BMGLLBRAF | |
| SCHEMBL27196351 | 0.78 | ULK1 (0.44) | MGLLULK1 | |
| SCHEMBL28340729 | 0.73 | KMT2A (0.51) | SMN1; SMN2KDM2BMGLLALDH1A1 | |
| SCHEMBL24529101 | 0.70 | SMYD3 (0.78) | SMYD3SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL19701229 | 0.69 | SMYD3 (1.00) | SMYD3SMN1; SMN2 | |
| SCHEMBL21489836 | 0.69 | SMYD3 (1.00) | SMYD3SMN1; SMN2 | |
| SCHEMBL5489310 | 0.69 | L3MBTL1 (0.45) | SMN1; SMN2KDM2BKDM4EALDH1A1 | |
| SCHEMBL16578349 | 0.68 | MGLL (0.46) | SMYD3SMN1; SMN2MGLLBRAF | |
| SCHEMBL45866 | 0.68 | PARP1 (0.57) | SMYD3LOXL2 | |
| SCHEMBL3890873 | 0.68 | CNR2 (0.51) | SMYD3SMN1; SMN2MGLLALDH1A1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170233872-A1 | ENVIRONMENTALLY FRIENDLY CORROSION INHIBITORS FOR HIGH TEMPERATURE APPLICATIONS | HALLIBURTON ENERGY SERVICES, INC. | 2017-08-17 | — | — | US | disclosed |