Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6255125 | 0.91 | ACLY (0.43) | TSHRACLYACACBACACAPPARA | |
| SCHEMBL5526119 | 0.89 | ACLY (0.45) | TSHRACLYACACBACACAPPARA | |
| Hydrochloric Acid SCHEMBL864764 | 0.87 | ACLY (0.43) | TSHRACLYACACBACACAPPARA | |
| SCHEMBL15012611 | 0.85 | MEN1 (0.48) | MEN1KMT2ATSHRMAPK1ACLY | |
| SCHEMBL6258950 | 0.83 | ACLY (0.45) | TSHRACLYACACBACACAPPARA | |
| Tetraethylene Glycol SCHEMBL4886960 | 0.82 | MEN1 (0.55) | MEN1KMT2ATSHRMAPK1THRB | |
| Triethylene Glycol SCHEMBL1640973 | 0.82 | MEN1 (0.55) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL5520099 | 0.81 | PPARA (0.49) | TSHRACLYACACBACACAPPARA | |
| SCHEMBL7632628 | 0.80 | TSHR (0.41) | MEN1KMT2ATSHRMAPK1ACLY | |
| Pivalate SCHEMBL11109449 | 0.80 | TSHR (0.53) | MEN1KMT2ATSHRMAPK1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328619-B1 | POLYMERIC BENZYL CARBONATE-DERIVATIVES | Baxalta GmbH (CH) | 2016-12-07 | — | — | EP | disclosed |
| US-8962549-B2 | Polymeric benzyl carbonate-derivatives | BAXTER INTERNATIONAL INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-20140128445-A1 | POLYMERIC BENZYL CARBONATE-DERIVATIVES | BAXTER HEALTHCARE SA (CH) | 2014-05-08 | — | — | US | disclosed |
| US-8653131-B2 | Polymeric benzyl carbonate-derivatives | BAXTER HEALTHCARE S.A. (CH) | 2014-02-18 | — | — | US | disclosed |
| EP-2328619-A2 | POLYMERIC BENZYL CARBONATE-DERIVATIVES | Baxter International Inc. (US) | 2011-06-08 | — | — | EP | disclosed |
| WO-2010022320-A2 | POLYMERIC BENZYL CARBONATE-DERIVATIVES | BAXTER INTERNATIONAL INC. (US) | 2010-02-25 | — | — | WO | disclosed |
| US-20100048483-A1 | POLYMERIC BENZYL CARBONATE-DERIVATIVES | BAXTER HEALTHCARE S.A. (CH) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048483-A1 | POLYMERIC BENZYL CARBONATE-DERIVATIVES | SI, SLC1A5, BCAT1 | MEN1 1541/4885KMT2A 1035/4885TSHR 4553/4885 |
| US-20140128445-A1 | POLYMERIC BENZYL CARBONATE-DERIVATIVES | SI, SLC1A5, BCAT1 | MEN1 1541/4885KMT2A 1035/4885TSHR 4553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.