Tetraethylene Glycol

Tetraethylene Glycol

SCHEMBL4886960

CC(C)(C)C(=O)O.CC(C)(C)C(=O)O.OCCOCCOCCOCCO

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
TSHR P16473 5/20 0.50
MAPK1 P28482 1/20 0.50
THRB P10828 1/20 0.43
HTT P42858 1/20 0.43
MAPT P10636 1/20 0.43
ALDH1A1 P00352 4/20 0.42
CYP4F2 P78329 1/20 0.35
CYP4A11 Q02928 1/20 0.35
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PPARA Q07869 3/20 0.32
PPARG P37231 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triethylene Glycol SCHEMBL1640973 1.00 MEN1 (0.55) MEN1KMT2ATSHRMAPK1THRB
Pivalate SCHEMBL4885836 0.97 TSHR (0.53) MEN1KMT2ATSHRMAPK1THRB
Pivalate SCHEMBL11109449 0.97 TSHR (0.53) MEN1KMT2ATSHRMAPK1THRB
Triethylene Glycol SCHEMBL11010343 0.86 MEN1 (0.50) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL15012611 0.84 MEN1 (0.48) MEN1KMT2ATSHRMAPK1THRB
Di(Hydroxyethyl)Ether SCHEMBL2528560 0.83 TSHR (0.48) MEN1KMT2ATSHRMAPK1THRB
Di(Hydroxyethyl)Ether SCHEMBL1171016 0.83 TSHR (0.48) MEN1KMT2ATSHRMAPK1THRB
Tetraethylene Glycol SCHEMBL23581563 0.82 MEN1 (0.46) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL1924848 0.82 MEN1 (0.46) MEN1KMT2ATSHRMAPK1THRB
Tetraethylene Glycol SCHEMBL29640412 0.82 MEN1 (0.46) MEN1KMT2ATSHRMAPK1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404258-B2 External preparation for the skin SHISEIDO COMPANY, LTD. (JP) 2013-03-26 US disclosed
US-8404258-B2 External preparation for the skin SHISEIDO COMPANY, LTD. (JP) 2013-03-26 US disclosed
US-20080293811-A1 External preparation for the the skin SHISEIDO COMPANY, LTD. (JP) 2008-11-27 US disclosed
US-20080293811-A1 External preparation for the the skin SHISEIDO COMPANY, LTD. (JP) 2008-11-27 US disclosed
EP-1430905-B1 SKIN TREATMENT COMPOSITION SHISEIDO CO LTD (JP) 2007-11-14 EP disclosed
EP-1430905-B1 SKIN TREATMENT COMPOSITION SHISEIDO CO LTD (JP) 2007-11-14 EP disclosed
EP-1430905-A4 EXTERNAL PREPARATION FOR THE SKIN SHISEIDO CO LTD (JP) 2006-06-14 EP disclosed
US-20040197361-A1 External preparation for the skin SHISEIDO COMPANY, LTD. (JP) 2004-10-07 US disclosed
US-20040197361-A1 External preparation for the skin SHISEIDO COMPANY, LTD. (JP) 2004-10-07 US disclosed
CN-1535162-A External preparation for skin ������������ʽ���� 2004-10-06 CN disclosed
EP-1430905-A1 EXTERNAL PREPARATION FOR THE SKIN SHISEIDO COMPANY LIMITED (JP) 2004-06-23 EP disclosed
EP-1430905-A1 EXTERNAL PREPARATION FOR THE SKIN SHISEIDO COMPANY LIMITED (JP) 2004-06-23 EP disclosed
WO-2003026698-A1 EXTERNAL PREPARATION FOR THE SKIN SHISEIDO COMPANY, LTD. (JP) 2003-04-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040197361-A1 External preparation for the skin CUTA, DDOST, DSG1 MEN1 4327/4885KMT2A 4360/4885TSHR 3564/4885
US-20080293811-A1 External preparation for the the skin CUTA, DDOST, DSG1 MEN1 4308/4885KMT2A 4423/4885TSHR 3558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.