Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetraethylene Glycol SCHEMBL4886960 | 1.00 | MEN1 (0.55) | MEN1KMT2ATSHRMAPK1THRB | |
| Pivalate SCHEMBL4885836 | 0.97 | TSHR (0.53) | MEN1KMT2ATSHRMAPK1THRB | |
| Pivalate SCHEMBL11109449 | 0.97 | TSHR (0.53) | MEN1KMT2ATSHRMAPK1THRB | |
| Triethylene Glycol SCHEMBL11010343 | 0.86 | MEN1 (0.50) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL15012611 | 0.84 | MEN1 (0.48) | MEN1KMT2ATSHRMAPK1THRB | |
| Di(Hydroxyethyl)Ether SCHEMBL2528560 | 0.83 | TSHR (0.48) | MEN1KMT2ATSHRMAPK1THRB | |
| Di(Hydroxyethyl)Ether SCHEMBL1171016 | 0.83 | TSHR (0.48) | MEN1KMT2ATSHRMAPK1THRB | |
| Tetraethylene Glycol SCHEMBL23581563 | 0.82 | MEN1 (0.46) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL1924848 | 0.82 | MEN1 (0.46) | MEN1KMT2ATSHRMAPK1THRB | |
| Tetraethylene Glycol SCHEMBL29640412 | 0.82 | MEN1 (0.46) | MEN1KMT2ATSHRMAPK1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404258-B2 | External preparation for the skin | SHISEIDO COMPANY, LTD. (JP) | 2013-03-26 | — | — | US | disclosed |
| US-8404258-B2 | External preparation for the skin | SHISEIDO COMPANY, LTD. (JP) | 2013-03-26 | — | — | US | disclosed |
| US-20110098231-A1 | Skin Cosmetic | SHISEIDO COMPANY, LTD. (JP) | 2011-04-28 | — | — | US | disclosed |
| EP-2168568-A1 | SKIN COSMETIC | Shiseido Company, Limited (JP) | 2010-03-31 | — | — | EP | disclosed |
| US-20090258964-A1 | Skin Cosmetic | SHISEIDO COMPANY, LTD. (JP) | 2009-10-15 | — | — | US | disclosed |
| US-20080293811-A1 | External preparation for the the skin | SHISEIDO COMPANY, LTD. (JP) | 2008-11-27 | — | — | US | disclosed |
| US-20080293811-A1 | External preparation for the the skin | SHISEIDO COMPANY, LTD. (JP) | 2008-11-27 | — | — | US | disclosed |
| EP-1430905-B1 | SKIN TREATMENT COMPOSITION | SHISEIDO CO LTD (JP) | 2007-11-14 | — | — | EP | disclosed |
| EP-1430905-B1 | SKIN TREATMENT COMPOSITION | SHISEIDO CO LTD (JP) | 2007-11-14 | — | — | EP | disclosed |
| EP-1430905-A4 | EXTERNAL PREPARATION FOR THE SKIN | SHISEIDO CO LTD (JP) | 2006-06-14 | — | — | EP | disclosed |
| US-20040197361-A1 | External preparation for the skin | SHISEIDO COMPANY, LTD. (JP) | 2004-10-07 | — | — | US | disclosed |
| US-20040197361-A1 | External preparation for the skin | SHISEIDO COMPANY, LTD. (JP) | 2004-10-07 | — | — | US | disclosed |
| CN-1535162-A | External preparation for skin | ������������ʽ���� | 2004-10-06 | — | — | CN | disclosed |
| EP-1430905-A1 | EXTERNAL PREPARATION FOR THE SKIN | SHISEIDO COMPANY LIMITED (JP) | 2004-06-23 | — | — | EP | disclosed |
| EP-1430905-A1 | EXTERNAL PREPARATION FOR THE SKIN | SHISEIDO COMPANY LIMITED (JP) | 2004-06-23 | — | — | EP | disclosed |
| WO-2003026698-A1 | EXTERNAL PREPARATION FOR THE SKIN | SHISEIDO COMPANY, LTD. (JP) | 2003-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258964-A1 | Skin Cosmetic | CUTA, DEGS1, ALAD | MEN1 1235/4885KMT2A 3368/4885TSHR 4285/4885 |
| US-20040197361-A1 | External preparation for the skin | CUTA, DDOST, DSG1 | MEN1 4327/4885KMT2A 4360/4885TSHR 3564/4885 |
| US-20080293811-A1 | External preparation for the the skin | CUTA, DDOST, DSG1 | MEN1 4308/4885KMT2A 4423/4885TSHR 3558/4885 |
| US-20110098231-A1 | Skin Cosmetic | CUTA, DEGS1, ALAD | MEN1 1235/4885KMT2A 3368/4885TSHR 4285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.