Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19249089 | 0.72 | TDO2 (0.47) | — | |
| SCHEMBL22084443 | 0.71 | BACE1 (0.40) | SMN1; SMN2 | |
| SCHEMBL19249331 | 0.67 | CYP1A2 (0.43) | ALOX15 | |
| SCHEMBL22083946 | 0.66 | — | — | |
| SCHEMBL19249327 | 0.65 | IDO1 (0.33) | — | |
| SCHEMBL22083949 | 0.63 | TAAR1 (0.35) | — | |
| SCHEMBL22083943 | 0.63 | OPRM1 (0.31) | — | |
| SCHEMBL22084441 | 0.61 | POLB (0.48) | SMN1; SMN2 | |
| SCHEMBL19454978 | 0.59 | ALOX15 (0.39) | ALOX15SMN1; SMN2 | |
| SCHEMBL21374456 | 0.59 | ALOX15 (0.39) | ALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133258-A1 | 1H-INDAZOLE DERIVATIVE AND USE THEREOF AS IDO INHIBITOR | 西华大学 | 2017-08-10 | — | — | WO | disclosed |