Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 4/20 | 0.36 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.35 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19249261 | 0.86 | IDO1 (0.36) | MAPTIDO1 | |
| SCHEMBL19249331 | 0.85 | CYP1A2 (0.43) | KDM4EMAPTLMNAIDO1 | |
| SCHEMBL19249347 | 0.84 | ALDH1A1 (0.45) | HSD17B10KDM4EHPGDGAAMAPT | |
| SCHEMBL4792453 | 0.79 | BACE1 (0.51) | BACE1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL23073193 | 0.78 | MAPT (0.48) | GAAMAPTAPPLMNAHTT | |
| SCHEMBL1519151 | 0.75 | SMN1; SMN2 (0.47) | BACE1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL3235742 | 0.75 | SMN1; SMN2 (0.47) | BACE1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL18930487 | 0.75 | SMN1; SMN2 (0.50) | HSD17B10KDM4EHPGDTSHRSMN1; SMN2 | |
| SCHEMBL22083868 | 0.74 | CDK7 (0.34) | — | |
| SCHEMBL22083943 | 0.73 | OPRM1 (0.31) | MAPTIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020113816-A1 | 4-AROMATIC HETEROCYCLIC SUBSTITUTED INDAZOLE AND USE THEREOF AS IDO/TDO DUAL INHIBITOR | 西华大学 | 2020-06-11 | — | — | WO | disclosed |