Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22050218 | 0.76 | MPO (0.33) | GPR84 | |
| SCHEMBL15636281 | 0.76 | CCNT1 (0.34) | GPR84PIM1 | |
| Hydrochloric Acid SCHEMBL21988072 | 0.74 | MPO (0.32) | GPR84 | |
| SCHEMBL22050219 | 0.72 | CSNK2A2 (0.38) | — | |
| SCHEMBL29958049 | 0.72 | TRIM24 (0.45) | GPR84PIM1PIM3PIM2 | |
| SCHEMBL21988074 | 0.71 | STING1 (0.33) | — | |
| SCHEMBL16727201 | 0.69 | GPR84 (0.40) | ATMHTR1ADRD2HTR2AHTR7 | |
| SCHEMBL3221554 | 0.69 | GPR84 (0.58) | ATMHTR2ARENARGPR84 | |
| SCHEMBL15730096 | 0.69 | GPR84 (0.58) | TDO2ATMHTR1ADRD2HTR2A | |
| SCHEMBL22050704 | 0.69 | ALDH1A1 (0.41) | ATMHTR1AHTR7PIM1PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133664-A1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT， AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |