Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 10/20 | 0.41 |
| ▸ | PIM1 | P11309 | 8/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956158 | 0.79 | TRIM24 (0.62) | TRIM24TRIM33CYP2A6IMPDH2KMT2A | |
| SCHEMBL1092989 | 0.76 | TRIM24 (0.64) | TRIM24TRIM33CYP2A6IMPDH2KMT2A | |
| SCHEMBL2534005 | 0.73 | GPR84 (0.53) | TRIM24TRIM33CYP2A6IMPDH2KMT2A | |
| SCHEMBL19249969 | 0.72 | TDO2 (0.33) | PIM3PIM1PIM2GPR84 | |
| SCHEMBL22050218 | 0.72 | MPO (0.33) | IMPDH2GPR84 | |
| SCHEMBL15636281 | 0.72 | CCNT1 (0.34) | PIM1CCNT1CDK9HASPINGPR84 | |
| SCHEMBL22050219 | 0.71 | CSNK2A2 (0.38) | — | |
| SCHEMBL29956329 | 0.71 | CYP2A6 (0.41) | CYP2A6IMPDH2KMT2ACCNT1CDK9 | |
| Hydrochloric Acid SCHEMBL21988072 | 0.70 | MPO (0.32) | IMPDH2GPR84 | |
| SCHEMBL21356468 | 0.70 | HTR1A (0.40) | TRIM24TRIM33CYP2A6IMPDH2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |