SCHEMBL19251435

SCHEMBL19251435

CCC1=Cc2nccnc2S(=O)(=O)N1c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRIA2 P42262 1/20 0.32
SHMT2 P34897 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19251425 0.82 LMNA (0.36) GRIA2
SCHEMBL19251605 0.67 LMNA (0.34)
SCHEMBL19251433 0.66 PIK3R1 (0.36)
SCHEMBL19252647 0.62 PIK3R1 (0.37)
SCHEMBL19251617 0.59 PIK3CD (0.37)
SCHEMBL19252631 0.58 PIK3CD (0.42)
SCHEMBL26446137 0.55 DHFR (0.32)
SCHEMBL17350294 0.53 CA12 (0.51)
SCHEMBL1906019 0.50 POLB (0.52)
SCHEMBL29483355 0.50 KDM4E (0.54)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017133655-A1 BENZOTHIAZINE AND BENZOTHIADIAZINE COMPOUNDS AND PREPARATION AND USE 浙江大学 2017-08-10 WO disclosed