Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1844995 | 0.87 | NPC1 (0.50) | RAB9ASIGMAR1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL13547569 | 0.84 | TRPC5 (0.49) | ALDH1A1POLBSIGMAR1MEN1KMT2A | |
| SCHEMBL8245902 | 0.83 | ALDH1A1 (0.51) | ALDH1A1CNR1SIGMAR1MEN1KMT2A | |
| SCHEMBL14924426 | 0.83 | MAPT (0.55) | ALDH1A1CNR1SIGMAR1SMN1; SMN2KAT2B | |
| SCHEMBL31606858 | 0.81 | LMNA (0.54) | ALDH1A1CNR1SIGMAR1KMT2ATP53 | |
| SCHEMBL14924008 | 0.79 | LMNA (0.47) | RAB9AALDH1A1CNR1POLBSIGMAR1 | |
| SCHEMBL19012756 | 0.75 | SIGMAR1 (0.45) | POLBSIGMAR1ALOX15TP53USP2 | |
| SCHEMBL30969324 | 0.75 | HDAC6 (0.52) | ALDH1A1CNR1POLBMEN1KMT2A | |
| SCHEMBL28783674 | 0.75 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL306744 | 0.74 | LMNA (0.69) | RAB9AALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE46511-E1 | Fused pyrimidine derivatives for inhibition of tyrosine kinase activity | HANMI SCIENCE CO., LTD. (KR) | 2017-08-15 | — | — | US | disclosed |