Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MDH1 | P40925 | 2/20 | 0.40 |
| ▸ | MDH2 | P40926 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18517387 | 0.85 | CNR2 (0.53) | LOXL2CYP4F2CYP4A11TSHRALDH1A1 | |
| SCHEMBL19254961 | 0.84 | KIF11 (0.45) | ALDH1A1POLBRAB9ATAS1R3TAS1R1 | |
| SCHEMBL1787753 | 0.82 | LOXL2 (0.51) | LOXL2CYP4F2CYP4A11TSHRALDH1A1 | |
| SCHEMBL19177191 | 0.82 | MAPT (0.50) | LOXL2TSHRALDH1A1POLBRAB9A | |
| SCHEMBL14817359 | 0.79 | LOXL2 (0.43) | LOXL2CYP4F2CYP4A11TSHRALDH1A1 | |
| SCHEMBL1787501 | 0.78 | ACHE (0.59) | LOXL2CYP4F2CYP4A11TSHRALDH1A1 | |
| SCHEMBL2892597 | 0.78 | TSHR (0.53) | LOXL2CYP4F2CYP4A11TSHRALDH1A1 | |
| Butane SCHEMBL27366277 | 0.78 | ALDH1A1 (0.62) | LOXL2ALDH1A1POLBTAS1R3TAS1R1 | |
| SCHEMBL548002 | 0.77 | TSHR (0.52) | LOXL2CYP4F2CYP4A11TSHRALDH1A1 | |
| SCHEMBL18717451 | 0.76 | CYP4F2 (0.58) | LOXL2CYP4F2CYP4A11TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732078-B2 | Therapeutic use of imidazopyridine derivatives | SANOFI (FR) | 2017-08-15 | — | — | US | disclosed |