Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19254595 | 0.84 | LOXL2 (0.47) | ACHEALDH1A1POLBTAS1R3TAS1R1 | |
| SCHEMBL3433869 | 0.80 | KIF11 (0.49) | KIF11ACHEHPGDALDH1A1POLB | |
| SCHEMBL309330 | 0.76 | ACHE (0.65) | KIF11ACHEALDH1A1 | |
| SCHEMBL19261303 | 0.76 | PARP1 (0.50) | KIF11ACHEALDH1A1POLBMAPT | |
| SCHEMBL548539 | 0.74 | ACHE (0.53) | KIF11ACHEALDH1A1MAOBLMNA | |
| SCHEMBL24377249 | 0.73 | ALDH1A1 (0.42) | KIF11ALDH1A1POLBTAS1R3TAS1R1 | |
| SCHEMBL18994837 | 0.73 | CA1 (0.41) | KIF11ALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL22024010 | 0.73 | KCNN4 (0.40) | KIF11ACHE | |
| SCHEMBL19483142 | 0.73 | SCN5A (0.44) | KIF11 | |
| SCHEMBL19728363 | 0.73 | TSHR (0.46) | ALDH1A1MAOBRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732078-B2 | Therapeutic use of imidazopyridine derivatives | SANOFI (FR) | 2017-08-15 | — | — | US | disclosed |