SCHEMBL19255485

SCHEMBL19255485

Ic1ccccc1-c1nnnn1I

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 10/20 0.55
ALDH1A1 P00352 6/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
TSHR P16473 2/20 0.34
P2RX7 Q99572 2/20 0.33
LMNA P02545 2/20 0.33
HTT P42858 1/20 0.33
DCTPP1 Q9H773 1/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20375446 0.81 KCNN4 (0.46) KCNN4ALDH1A1SMN1; SMN2TSHRP2RX7
SCHEMBL20684736 0.79 KCNN4 (0.54) KCNN4ALDH1A1SMN1; SMN2TSHRP2RX7
SCHEMBL19254853 0.77 P2RX7 (0.37) KCNN4ALDH1A1SMN1; SMN2TSHRP2RX7
SCHEMBL19255489 0.77 ALDH1A1 (0.36) KCNN4ALDH1A1P2RX7
SCHEMBL19255487 0.77 KCNN4 (0.35) KCNN4ALDH1A1P2RX7
SCHEMBL23113874 0.74 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2TSHRP2RX7LMNA
SCHEMBL21465920 0.73 P2RX7 (0.43) KCNN4P2RX7
SCHEMBL19255486 0.73 KCNN4 (0.35) KCNN4ALDH1A1SMN1; SMN2TSHRP2RX7
SCHEMBL16919493 0.72 KCNN4 (0.69) KCNN4
SCHEMBL16919545 0.72 KCNN4 (0.69) KCNN4ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11832511-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-11-28 US disclosed
US-11678566-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-06-13 US disclosed
US-20210167303-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION (KR) 2021-06-03 US disclosed
US-11011710-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-05-18 US disclosed
US-10944063-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-03-09 US disclosed
US-10941171-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-03-09 US disclosed
US-10923667-B2 Organometallic compound, composition containing the organometallic compound, and organic light-emitting device including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-02-16 US disclosed
US-20210028374-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-01-28 US disclosed
US-20200358007-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2020-11-12 US disclosed
US-20200199164-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG SDI CO., LTD. (KR) 2020-06-25 US disclosed
US-10326086-B2 Organometallic compound, composition containing the organometallic compound, and organic light-emitting device including the organometallic compound or composition SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-06-18 US disclosed
US-9735376-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210028374-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME L1CAM, AP1M1, PYM1 KCNN4 1721/4885ALDH1A1 368/4885SMN1; SMN2 1044/4885
US-10944063-B2 Organometallic compound and organic light-emitting device including the same CRY1, LEF1, POU2F1 KCNN4 3121/4885ALDH1A1 11/4885SMN1; SMN2 3533/4885
US-10326086-B2 Organometallic compound, composition containing the organometallic compound, and organic light-emitting device including the organometallic compound or composition ORC3, LEF1, AP1M1 KCNN4 3781/4885ALDH1A1 258/4885SMN1; SMN2 3693/4885
US-11678566-B2 Organometallic compound and organic light-emitting device including the same L1CAM, AP1M1, PYM1 KCNN4 1721/4885ALDH1A1 368/4885SMN1; SMN2 1044/4885
US-20200358007-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME L1CAM, L3MBTL1, FOXM1 KCNN4 3144/4885ALDH1A1 135/4885SMN1; SMN2 938/4885
US-11832511-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound L1CAM, NOM1, FOXM1 KCNN4 3297/4885ALDH1A1 110/4885SMN1; SMN2 2302/4885
US-20200199164-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND L1CAM, MEN1, NOM1 KCNN4 3513/4885ALDH1A1 287/4885SMN1; SMN2 1178/4885
US-20210167303-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND L1CAM, NOM1, FOXM1 KCNN4 3297/4885ALDH1A1 110/4885SMN1; SMN2 2302/4885
US-11011710-B2 Organometallic compound and organic light-emitting device including the same L1CAM, L3MBTL1, FOXM1 KCNN4 3144/4885ALDH1A1 135/4885SMN1; SMN2 938/4885
US-10941171-B2 Organometallic compound and organic light-emitting device including the same CRY1, LEF1, POU2F1 KCNN4 3121/4885ALDH1A1 11/4885SMN1; SMN2 3533/4885
US-10923667-B2 Organometallic compound, composition containing the organometallic compound, and organic light-emitting device including the organometallic compound ORC3, LEF1, ODC1 KCNN4 3349/4885ALDH1A1 185/4885SMN1; SMN2 3780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.