SCHEMBL19255795

SCHEMBL19255795

Fc1cc(F)c2[nH]nc(-c3nc(Cl)c(F)c(Cl)n3)c2c1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.32
EGFR P00533 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19255794 0.90
SCHEMBL19255585 0.73 REN (0.34)
SCHEMBL19255693 0.72 EGFR (0.31) EGFR
SCHEMBL19886409 0.71 ADORA1 (0.49)
SCHEMBL19250615 0.70 HCAR2 (0.34)
SCHEMBL19255963 0.69 HCAR2 (0.32)
SCHEMBL19886542 0.68 TNKS (0.32)
SCHEMBL786095 0.68 GPR84 (0.40) GPR84EGFR
SCHEMBL13122194 0.66 ADORA2A (0.49) GPR84EGFR
SCHEMBL19249596 0.66 GPR84 (0.39) GPR84EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017133670-A1 PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA SAVIRA PHARMACEUTICALS GMBH (AT) 2017-08-10 WO disclosed