SCHEMBL19255963

SCHEMBL19255963

CCCCCc1nc(-c2n[nH]c3c(F)cc(F)cc23)nc(N)c1F

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19250615 0.97 HCAR2 (0.34) HCAR2
SCHEMBL19255585 0.88 REN (0.34)
SCHEMBL19255728 0.77 MPO (0.31)
SCHEMBL19255693 0.71 EGFR (0.31)
SCHEMBL19886542 0.69 TNKS (0.32)
SCHEMBL786095 0.66 GPR84 (0.40)
SCHEMBL13122140 0.65 GPR84 (0.41)
SCHEMBL19255794 0.65
SCHEMBL19255949 0.65 SGK1 (0.31)
SCHEMBL19255202 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017133670-A1 PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA SAVIRA PHARMACEUTICALS GMBH (AT) 2017-08-10 WO disclosed