Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL398570 | 0.80 | ENPP2 (0.50) | CA2CA1 | |
| SCHEMBL20300446 | 0.77 | CA2 (0.42) | CA2CA1PSIP1CA12CA4 | |
| SCHEMBL97582 | 0.76 | CA1 (0.52) | CA2CA1 | |
| SCHEMBL22694011 | 0.76 | ENPP2 (0.38) | CA2CA1CA12CA6CA5A | |
| SCHEMBL22363546 | 0.76 | CA2 (0.44) | CA2CA1CA12CA4CA6 | |
| SCHEMBL13816084 | 0.76 | CA2 (0.56) | CA2PSIP1 | |
| SCHEMBL18552646 | 0.74 | TRPA1 (0.43) | CA2CA1PSIP1CA12CA4 | |
| SCHEMBL21277670 | 0.74 | PSIP1 (0.58) | CA2CA1PSIP1CA12CA4 | |
| SCHEMBL3539406 | 0.74 | CYP3A4 (0.52) | CA2CA1CA12CA4CA6 | |
| SCHEMBL20323503 | 0.73 | DRD1 (0.42) | CA2CA1PSIP1CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136466-A1 | HEME PROTEIN CATALYSTS FOR CARBON-SILICON BOND FORMATION IN VITRO AND IN VIVO | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2017-08-10 | — | — | WO | disclosed |