Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 3/20 | 0.41 |
| ▸ | CPT2 | P23786 | 2/20 | 0.41 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12524010 | 0.78 | ACLY (0.43) | ALDH1A1CYP2C19HIF1ACYP2D6TSHR | |
| SCHEMBL18798915 | 0.78 | ACLY (0.43) | ALDH1A1CYP2C19HIF1ACYP2D6TSHR | |
| SCHEMBL23772237 | 0.78 | CYP2C19 (0.46) | ALDH1A1CYP2C19HIF1ACYP2D6TSHR | |
| SCHEMBL12528005 | 0.76 | ACLY (0.58) | ALDH1A1CYP2C19HIF1ACYP2D6TSHR | |
| SCHEMBL12458905 | 0.72 | ACLY (0.39) | ALDH1A1CYP2C19HIF1ACYP2D6TSHR | |
| SCHEMBL18798472 | 0.72 | ACLY (0.39) | ALDH1A1CYP2C19HIF1ACYP2D6TSHR | |
| SCHEMBL18798923 | 0.71 | ACLY (0.38) | ALDH1A1CYP2C19HIF1ACYP2D6TSHR | |
| SCHEMBL12458904 | 0.71 | ACLY (0.38) | ALDH1A1CYP2C19HIF1ACYP2D6TSHR | |
| SCHEMBL22421672 | 0.69 | CYP2C19 (0.43) | ALDH1A1CYP2C19HIF1ACYP2D6TSHR | |
| SCHEMBL2446996 | 0.65 | ALDH1A1 (0.53) | ALDH1A1CYP2C19HIF1ACYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170232013-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF MUSCULOSKELETAL RELATED DISEASES AND DISORDERS USING METAL ION-CITRATE ANALOG COMPLEXES | THE CHARLOTTE-MECKLENBURG HOSPITAL AUTHORITY D/B/A ATRIUM HEALTH | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170232013-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF MUSCULOSKELETAL RELATED DISEASES AND DISORDERS USING METAL ION-CITRATE ANALOG COMPLEXES | CS, ACLY, CA5A | ALDH1A1 1294/4885CYP2C19 878/4885HIF1A 1224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.