Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 14/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 14/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19258971 | 0.68 | RPS6KA5 (0.36) | ALDH1A1KDM4E | |
| SCHEMBL24695579 | 0.64 | AGBL2 (0.46) | ALDH1A1KDM4EAGBL2GAA | |
| SCHEMBL30231011 | 0.63 | CA12 (0.41) | ALDH1A1KDM4EHTT | |
| SCHEMBL19259003 | 0.61 | HDAC8 (0.38) | KDM4EPOLB | |
| SCHEMBL27284155 | 0.61 | ALDH1A1 (0.63) | ALDH1A1KDM4EPOLBGAAHTT | |
| SCHEMBL19258560 | 0.61 | GRIN1 (0.34) | ALDH1A1GRIN1GRIN2B | |
| SCHEMBL11631751 | 0.60 | HRH4 (0.39) | ALDH1A1KDM4EPOLBPKMAGBL2 | |
| SCHEMBL24609261 | 0.60 | ALDH1A1 (0.31) | ALDH1A1KDM4EGRIN1GRIN2B | |
| SCHEMBL18366009 | 0.60 | ALDH1A1 (0.39) | ALDH1A1KDM4EAGBL2HTT | |
| SCHEMBL21730132 | 0.59 | ALDH1A1 (0.42) | ALDH1A1KDM4EPOLBPKMAGBL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133657-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |