Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17376106 | 0.82 | HTT (0.33) | HCAR3MEN1LMNAMAPTKMT2A | |
| SCHEMBL19268056 | 0.80 | HCAR3 (0.44) | HCAR3AOC3PARP1LMNACYP3A4 | |
| Hydrochloric Acid SCHEMBL4365233 | 0.73 | NNMT (0.32) | MEN1KMT2AHSD17B10 | |
| SCHEMBL17774956 | 0.73 | IKBKB (0.41) | HCAR3MEN1NR1I2LMNACHRM2 | |
| SCHEMBL14852700 | 0.73 | HCAR3 (0.75) | HCAR3AOC3TRPV1KDM4E | |
| SCHEMBL17774951 | 0.71 | HCAR3 (0.35) | HCAR3MEN1NR1I2LMNACHRM2 | |
| SCHEMBL21318032 | 0.70 | AR (0.49) | HCAR3AOC3ARLMNAMAPT | |
| SCHEMBL25239937 | 0.70 | NNMT (0.49) | HCAR3 | |
| SCHEMBL31140636 | 0.70 | NNMT (0.49) | HCAR3 | |
| SCHEMBL17376093 | 0.69 | ALDH1A1 (0.49) | HCAR3LMNACYP3A4MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170240514-A1 | Small Molecule Agonists of Neurotensin Receptor 1 | Sanford Burnham Prebys Medical Discovery Institute | 2017-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170240514-A1 | Small Molecule Agonists of Neurotensin Receptor 1 | NTSR1, NTSR2, VIPR1 | HCAR3 132/4885AOC3 2357/4885AR 702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.