Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 10/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.37 |
| ▸ | GJB2 | P29033 | 4/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.35 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.35 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.34 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.34 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19276589 | 0.98 | GJB2 (0.37) | PTPN1PTPN2PTPN6PTPN11GJB2 | |
| SCHEMBL19276741 | 0.91 | PTPN1 (0.38) | PTPN1PTPN2PTPN6PTPN11GJB2 | |
| SCHEMBL19277319 | 0.91 | PTPN1 (0.38) | PTPN1PTPN2PTPN6PTPN11GJB2 | |
| SCHEMBL19276590 | 0.90 | GJB2 (0.38) | PTPN1PTPN2PTPN6PTPN11GJB2 | |
| SCHEMBL17636513 | 0.88 | LGALS9 (0.38) | PTPN1PTPN2PTPN6PTPN11GJB2 | |
| SCHEMBL17636468 | 0.86 | FGF2 (0.36) | PTPN1PTPN2PTPN6PTPN11NT5E | |
| SCHEMBL19277202 | 0.86 | LGALS3 (0.44) | PTPN1GJB2NT5ELGALS3LGALS4 | |
| SCHEMBL17636461 | 0.84 | FGF2 (0.37) | PTPN1PTPN2PTPN6PTPN11GJB2 | |
| SCHEMBL17636515 | 0.84 | FGF2 (0.37) | PTPN1PTPN2PTPN6PTPN11GJB2 | |
| SCHEMBL17087681 | 0.84 | PTPN1 (0.44) | PTPN1PTPN2PTPN6PTPN11GJB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170239341-A1 | VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 8 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2017-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170239341-A1 | VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 8 | LGALS8, SIGLEC7, FUT5 | PTPN1 1072/4885PTPN2 1305/4885PTPN6 1339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.