Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31279720 | 0.80 | ALDH1A1 (0.37) | ALDH1A1ABL1BCRLMNAHTT | |
| SCHEMBL19252020 | 0.80 | ALDH1A1 (0.37) | ALDH1A1ABL1BCRLMNAHTT | |
| SCHEMBL19268782 | 0.74 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL19278216 | 0.71 | ABL1 (0.36) | ALDH1A1ABL1BCRLMNAHTT | |
| SCHEMBL19273979 | 0.70 | METAP2 (0.31) | — | |
| SCHEMBL16340138 | 0.66 | ABL1 (0.36) | ALDH1A1ABL1BCRLMNAHTT | |
| SCHEMBL28391967 | 0.66 | ABL1 (0.40) | ALDH1A1ABL1BCRLMNAHTT | |
| SCHEMBL20536259 | 0.63 | ABL1 (0.42) | ALDH1A1ABL1BCRLMNAHTT | |
| SCHEMBL25320029 | 0.62 | PDE2A (0.33) | ALDH1A1LMNA | |
| SCHEMBL13579554 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017143291-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2017-08-24 | — | — | WO | disclosed |