Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19252020 | 1.00 | ALDH1A1 (0.37) | ALDH1A1JAK2PKMMCOLN3NPSR1 | |
| SCHEMBL19278217 | 0.80 | ALDH1A1 (0.35) | ALDH1A1NPSR1L3MBTL1ABL1BCR | |
| SCHEMBL5002087 | 0.80 | SRC (0.39) | ALDH1A1JAK2PKMMCOLN3NPSR1 | |
| SCHEMBL14321207 | 0.75 | HTR6 (0.42) | ALDH1A1ABL1BCRLMNAHTT | |
| SCHEMBL31279549 | 0.75 | SRC (0.38) | PKMSRCMAPTPIK3CDPIK3CA | |
| SCHEMBL19252466 | 0.75 | SRC (0.38) | PKMSRCMAPTPIK3CDPIK3CA | |
| SCHEMBL31279422 | 0.75 | HTR6 (0.42) | ALDH1A1ABL1BCRLMNAHTT | |
| SCHEMBL28391967 | 0.73 | ABL1 (0.40) | ALDH1A1NPSR1L3MBTL1ABL1BCR | |
| SCHEMBL5004901 | 0.73 | SRC (0.41) | ALDH1A1PKMNPSR1SRCMAPT | |
| SCHEMBL4308888 | 0.73 | PTGDR2 (0.42) | ALDH1A1PKMSRCMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119161324-A | Methods and compounds for restoring mutant p53 function | 皮姆维制药公司 | 2024-12-20 | — | — | CN | disclosed |