SCHEMBL19280735

SCHEMBL19280735

N#Cc1ccc(Oc2cccc(CO)c2)cc1C#N

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.54
MAOB P27338 2/20 0.53
AR P10275 4/20 0.47
ALDH1A1 P00352 2/20 0.45
HPGD P15428 2/20 0.45
PDE4B Q07343 1/20 0.44
LTA4H P09960 1/20 0.43
MAOA P21397 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
CYP11B1 P15538 1/20 0.41
CYP11B2 P19099 1/20 0.41
TTR P02766 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3568078 0.85 LTA4H (0.52) CYP19A1MAOBARALDH1A1HPGD
SCHEMBL6289952 0.84 CYP19A1 (0.54) CYP19A1MAOBARALDH1A1HPGD
SCHEMBL16310207 0.84 CYP19A1 (0.54) CYP19A1MAOBARALDH1A1HPGD
SCHEMBL6289949 0.84 CYP19A1 (0.54) CYP19A1MAOBARALDH1A1HPGD
SCHEMBL9746014 0.83 CYP19A1 (0.52) CYP19A1MAOBARALDH1A1HPGD
SCHEMBL9746473 0.83 CYP19A1 (0.52) CYP19A1MAOBARALDH1A1HPGD
SCHEMBL5145150 0.83 CYP19A1 (0.67) CYP19A1MAOBARALDH1A1HPGD
SCHEMBL1374021 0.83 CYP19A1 (0.67) CYP19A1MAOBARALDH1A1HPGD
SCHEMBL31168160 0.83 CYP19A1 (0.67) CYP19A1MAOBARALDH1A1HPGD
SCHEMBL3174815 0.83 CYP11B1 (0.56) CYP19A1MAOBPDE4BLTA4HCYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3521340-A1 A PHTHALONITRILE MONOMER MODIFIED BY ORGANOPHOSPHATE FRAGMENTS, A METHOD FOR OBTAINING SAME, A BINDER BASED THEREON, AND A PREPREG Joint Stock Company Scientific and Production Association "Unichimtek" (JSC PSA "Unichimtek) (RU) 2019-08-07 EP disclosed
US-20190218235-A1 Phthalonitrile Monomer Modified with Organophosphorus Fragments, a Method of Producing thereof, a Binder Based Thereon, and a Prepreg JOINT STOCK COMPANY SCIENTIFIC AND PRODUCTION ASSOCIATION "UNICHIMTEK" (JSC PSA "UNICHIMTEK") (RU) 2019-07-18 US disclosed
EP-3211023-A1 PHTHALONITRILE MONOMER MODIFIED WITH ORGANOSILICON FRAGMENTS Joint Stock Company Scientific and Production Association "Unichimtek" (JSC PSA "Unichimtek) (RU) 2017-08-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190218235-A1 Phthalonitrile Monomer Modified with Organophosphorus Fragments, a Method of Producing thereof, a Binder Based Thereon, and a Prepreg THEM6, NOTUM, PNN CYP19A1 1229/4885MAOB 1907/4885AR 2119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.