Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 7/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 2/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19287944 | 0.81 | TYMS (0.47) | XDHALDH1A1KMT2ATYMSNPC1 | |
| SCHEMBL19757295 | 0.78 | KIF11 (0.38) | KIF11SCN10AXDHALDH1A1TP53 | |
| SCHEMBL18735819 | 0.78 | KDM4E (0.46) | TNKSTNKS2PARP1ALDH1A1TYMS | |
| SCHEMBL16219519 | 0.75 | KDM4E (0.44) | KIF11SCN10AKCNH2TNKSTNKS2 | |
| SCHEMBL14346059 | 0.74 | MITF (0.43) | MITFALDH1A1TP53KMT2A | |
| SCHEMBL14346062 | 0.70 | LRRK2 (0.47) | SCN10AMITFALDH1A1TP53KMT2A | |
| SCHEMBL30618511 | 0.69 | SCN10A (0.66) | SCN10AKCNH2ALDH1A1 | |
| SCHEMBL13619366 | 0.69 | FABP6 (0.50) | KIF11SCN10AKCNH2ALDH1A1KMT2A | |
| SCHEMBL5679483 | 0.69 | SCN10A (0.66) | SCN10AKCNH2ALDH1A1 | |
| SCHEMBL24859285 | 0.69 | KIF11 (0.50) | KIF11SCN10AKCNH2TNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210130822-A1 | ANTISENSE OLIGOMER COMPOUNDS | SAREPTA THERAPEUTICS, INC. (US) | 2021-05-06 | — | — | US | disclosed |
| US-9744183-B2 | Nucleic acid prodrugs and methods of use thereof | WAVE LIFE SCIENCES LTD. (SG) | 2017-08-29 | — | — | US | disclosed |
| US-9744183-B2 | Nucleic acid prodrugs and methods of use thereof | WAVE LIFE SCIENCES LTD. (SG) | 2017-08-29 | — | — | US | disclosed |