Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.50 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | GHSR | Q92847 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTR1D | P28221 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24859286 | 0.82 | GHSR (0.39) | KIF11SCN10AKCNH2GHSRGABRA1 | |
| SCHEMBL10779485 | 0.78 | ALDH1A1 (0.44) | KIF11ALDH1A1SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL846855 | 0.76 | SCN10A (0.58) | KIF11SCN10AKCNH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL30577796 | 0.75 | KIF11 (0.65) | KIF11GHSRGABRA1GABRG2GABRB3 | |
| SCHEMBL25243502 | 0.75 | KIF11 (0.65) | KIF11GHSRGABRA1GABRG2GABRB3 | |
| SCHEMBL30577798 | 0.75 | KIF11 (0.65) | KIF11GHSRGABRA1GABRG2GABRB3 | |
| SCHEMBL29535 | 0.74 | KIF11 (0.81) | KIF11GHSRGABRA1GABRG2GABRB3 | |
| SCHEMBL29361452 | 0.74 | KIF11 (0.81) | KIF11GHSRGABRA1GABRG2GABRB3 | |
| Ammonia Solution, Strong SCHEMBL25176966 | 0.73 | KIF11 (0.78) | KIF11GHSRGABRA1GABRG2GABRB3 | |
| SCHEMBL846652 | 0.73 | SCN10A (0.78) | SCN10AKCNH2ALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230128450-A1 | NLRX1 LIGANDS | LANDOS BIOPHARMA, INC. (US) | 2023-04-27 | — | — | US | disclosed |
| US-11548885-B2 | NLRX1 ligands | LANDOS BIOPHARMA, INC. (US) | 2023-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11548885-B2 | NLRX1 ligands | NLRP3, NLRP1, NOD1 | KIF11 4349/4885SCN10A 3045/4885KCNH2 4439/4885 |
| US-20230128450-A1 | NLRX1 LIGANDS | NLRP3, NLRP1, NOD1 | KIF11 4349/4885SCN10A 3045/4885KCNH2 4439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.