Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | PLAU | P00749 | 2/20 | 0.62 |
| ▸ | MASP2 | O00187 | 1/20 | 0.62 |
| ▸ | THPO | P40225 | 1/20 | 0.62 |
| ▸ | F12 | P00748 | 2/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.59 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.59 |
| ▸ | F2 | P00734 | 4/20 | 0.59 |
| ▸ | APEX1 | P27695 | 1/20 | 0.59 |
| ▸ | F10 | P00742 | 2/20 | 0.57 |
| ▸ | F7 | P08709 | 1/20 | 0.57 |
| ▸ | F3 | P13726 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.56 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL10917300 | 0.97 | LMNA (0.94) | LMNAPLAUMASP2THPOF12 | |
| Hydrochloric Acid SCHEMBL4279969 | 0.97 | LMNA (0.94) | LMNAPLAUMASP2THPOF12 | |
| SCHEMBL537030 | 0.87 | LMNA (0.77) | LMNAPLAUMASP2THPOF12 | |
| SCHEMBL19286912 | 0.86 | ST14 (0.83) | LMNAPLAUF12PRSS1PRSS3 | |
| Hydrochloric Acid SCHEMBL30999366 | 0.84 | PRSS1 (0.78) | LMNAPLAUMASP2THPOF12 | |
| Hydrochloric Acid SCHEMBL392375 | 0.84 | PRSS1 (0.78) | LMNAPLAUMASP2THPOF12 | |
| SCHEMBL8973288 | 0.79 | WDR5 (0.80) | LMNAPLAUMASP2THPOF12 | |
| SCHEMBL394218 | 0.79 | WDR5 (0.80) | LMNAPLAUMASP2THPOF12 | |
| SCHEMBL150756 | 0.77 | PLAU (1.00) | LMNAPLAUMASP2THPOF12 | |
| Hydrochloric Acid SCHEMBL29182280 | 0.77 | PRSS1 (0.67) | LMNAPLAUMASP2THPOF12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 401 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878444-A | Method for preparing hexamidine di (isethionic acid) salt | 贵州中森医药有限公司 | 2024-11-01 | — | — | CN | claimed |
| CN-118221550-A | Preparation method of amidine compound dihydroxyethyl sulfonate and intermediate thereof | 上海睿智医药技术有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-113383039-B | Moisture curable polyolefin formulation | 陶氏环球技术有限责任公司 | 2023-09-26 | — | — | CN | claimed |
| US-20220098432-A1 | MOISTURE-CURABLE POLYOLEFIN FORMULATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-03-31 | — | — | US | claimed |
| EP-3924419-A1 | MOISTURE-CURABLE POLYOLEFIN FORMULATION | Dow Global Technologies LLC (US) | 2021-12-22 | — | — | EP | claimed |
| CN-113383039-A | Moisture curable polyolefin formulations | 陶氏环球技术有限责任公司 | 2021-09-10 | — | — | CN | claimed |
| WO-2020164004-A1 | MOISTURE-CURABLE POLYOLEFIN FORMULATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-08-20 | — | — | WO | claimed |
| CN-108966651-A | Indole amine 2,3-dioxygenase inhibitor and the preparation method and application thereof | 江苏豪森药业集团有限公司 | 2018-12-07 | — | — | CN | claimed |
| CN-108884063-A | Indole amine 2,3-dioxygenase inhibitor and the preparation method and application thereof | 江苏豪森药业集团有限公司 | 2018-11-23 | — | — | CN | claimed |
| CN-107304191-A | Indoleamine 2,3 dioxygenase inhibitors and preparation method and application | 上海翰森生物医药科技有限公司 | 2017-10-31 | — | — | CN | claimed |
| EP-0703216-B1 | Amidinophenol derivatives as protease inhibitors | ONO PHARMACEUTICAL CO (JP) | 1999-04-07 | — | — | EP | claimed |
| EP-0893437-A1 | TRYPTASE INHIBITOR AND NOVEL GUANIDINO DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-01-27 | — | — | EP | claimed |
| EP-0656349-B1 | Amidinophenol derivatives having phospholipase A2 inhibitory activity | ONO PHARMACEUTICAL CO (JP) | 1998-04-08 | — | — | EP | claimed |
| CN-1035998-C | Amidinophenol derivatives | ONO PHARMACEUTICA CO LTD (JP) | 1997-10-01 | — | — | CN | claimed |
| EP-0703216-A1 | Amidinophenol derivatives as protease inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-03-27 | — | — | EP | claimed |
| CN-1110679-A | Amidinophenol derivatives | ONO PHARMACEUTICA CO LTD (JP) | 1995-10-25 | — | — | CN | claimed |
| EP-0656349-A1 | Amidinophenol derivatives having phospholipase A2 inhibitory activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-06-07 | — | — | EP | claimed |
| EP-0094052-A2 | 1-(1,3-Dioxolan-2-yl-methyl)-1H-imidazoles and -1H-1,2,4-triazoles and their salts, process for their preparation, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-11-16 | — | — | EP | claimed |
| EP-0025119-B1 | NEMATIC CRYSTALLINE-LIQUID 5-ALKYL-2-(4-ACYLOXYPHENYL)-PYRIMIDINES FOR OPTO-ELECTRONIC ARRANGEMENTS AND PROCESS FOR THEIR PREPARATION | VEB Werk Für Fernsehelektronik im VEB Kombinat Mikroelektronik (DD) | 1983-05-25 | — | — | EP | claimed |
| EP-0009879-A1 | Enzyme derivatives for use in the treatment of venous thrombosis, compositions containing them and their preparation | BEECHAM GROUP PLC (GB) | 1980-04-16 | — | — | EP | claimed |