Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A known ✓ | P11388 | 1/20 | 0.52 |
| ▸ | TOP2B known ✓ | Q02880 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.94 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.64 |
| ▸ | F2 | P00734 | 4/20 | 0.64 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.64 |
| ▸ | APEX1 | P27695 | 1/20 | 0.64 |
| ▸ | PLAU | P00749 | 2/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | MASP2 | O00187 | 1/20 | 0.59 |
| ▸ | THPO | P40225 | 1/20 | 0.59 |
| ▸ | F12 | P00748 | 2/20 | 0.58 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.56 |
| ▸ | C1S | P09871 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | F10 | P00742 | 2/20 | 0.55 |
| ▸ | F7 | P08709 | 1/20 | 0.55 |
| ▸ | F3 | P13726 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL563315 | 0.97 | LMNA (1.00) | LMNAPRSS1F2PRSS3APEX1 | |
| Water SCHEMBL10917300 | 0.94 | LMNA (0.94) | LMNAPRSS1F2PRSS3APEX1 | |
| Hydrochloric Acid SCHEMBL392375 | 0.88 | PRSS1 (0.78) | LMNAPRSS1F2PRSS3APEX1 | |
| Hydrochloric Acid SCHEMBL30999366 | 0.88 | PRSS1 (0.78) | LMNAPRSS1F2PRSS3APEX1 | |
| SCHEMBL537030 | 0.85 | LMNA (0.77) | LMNAPRSS1F2PRSS3APEX1 | |
| SCHEMBL19286912 | 0.84 | ST14 (0.83) | LMNAPRSS1F2PRSS3PLAU | |
| Hydrochloric Acid SCHEMBL29182280 | 0.80 | PRSS1 (0.67) | LMNAPRSS1F2PRSS3APEX1 | |
| Hydrochloric Acid SCHEMBL538862 | 0.78 | PRSS1 (1.00) | LMNAPRSS1F2PRSS3APEX1 | |
| Hydrochloric Acid SCHEMBL236095 | 0.78 | PRSS1 (1.00) | LMNAPRSS1F2PRSS3APEX1 | |
| Hydrochloric Acid SCHEMBL7837112 | 0.77 | F12 (0.96) | LMNAPRSS1F2PLAUF12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120054594-A | Modified Y-type molecular sieve, preparation method thereof and hydrocracking catalyst | 中国石油天然气股份有限公司 | 2025-05-30 | — | — | CN | claimed |
| CN-119330899-A | Triphenylamine triazine compound, preparation method and application thereof in detection of explosive and medicines | 西南科技大学 | 2025-01-21 | — | — | CN | claimed |
| CN-118978512-A | 2-Hydroxy-3-pinonyl pyrimidine pH sensitive fluorescent probe and preparation method and application thereof | 南京林业大学 | 2024-11-19 | — | — | CN | claimed |
| CN-118086928-A | Method for electrochemical synthesis of pyrimidoindole derivative under mild condition | 湘潭大学 | 2024-05-28 | — | — | CN | claimed |
| CN-111690229-A | Anti-aging flame-retardant ABS plastic | 宁波保税区君一汽配科技有限公司 | 2020-09-22 | — | — | CN | claimed |
| CN-111484652-A | Degradable plastic rope | 界首市宏利塑料有限公司 | 2020-08-04 | — | — | CN | claimed |
| CN-111333958-A | High-durability plastic rope | 界首市宏利塑料有限公司 | 2020-06-26 | — | — | CN | claimed |
| CN-111320818-A | Anti-aging plastic rope | 界首市宏利塑料有限公司 | 2020-06-23 | — | — | CN | claimed |
| CN-110938353-A | Decorative coating for composite steel plate | 王磊 | 2020-03-31 | — | — | CN | claimed |
| CN-106946808-A | The synthetic method of benzo [1,3,5] triazole octanone derivative | 苏州大学 | 2017-07-14 | — | — | CN | claimed |
| EP-0313991-A2 | 5-Alkoxy-2-(4-alkoxyphenyl)pyrimidine, method for its preparation and use | CHISSO CORPORATION (JP) | 1989-05-03 | — | — | EP | claimed |
| EP-0025119-B1 | NEMATIC CRYSTALLINE-LIQUID 5-ALKYL-2-(4-ACYLOXYPHENYL)-PYRIMIDINES FOR OPTO-ELECTRONIC ARRANGEMENTS AND PROCESS FOR THEIR PREPARATION | VEB Werk Für Fernsehelektronik im VEB Kombinat Mikroelektronik (DD) | 1983-05-25 | — | — | EP | claimed |
| EP-0025119-A1 | Nematic crystalline-liquid 5-alkyl-2-(4-acyloxyphenyl)-pyrimidines for opto-electronic arrangements and process for their preparation | VEB Werk Für Fernsehelektronik im VEB Kombinat Mikroelektronik (DD) | 1981-03-18 | — | — | EP | claimed |
| JP-8333324-A | — | — | None | — | — | JP | disclosed |
| CN-122054801-A | Solar cell, preparation method thereof, photovoltaic module, power utilization device and power generation device | 宁德时代新能源科技股份有限公司 | 2026-05-15 | — | — | CN | disclosed |
| EP-4638448-A1 | CONJUGATES COMPRISING ANTIFUNGALS AND CASEIN KINASE (CK1) INHIBITORS AND METHODS OF USE THEREOF | Bright Angel Therapeutics Inc. (CA) | 2025-10-29 | — | — | EP | disclosed |
| US-4337244-A | COMPRISING A FIBRINOLYTIC ENZYME BLOCKED BY AN END GROUP REMOVABLE BY HYDROLYSIS | BEECHAM GROUP LIMITED (GB) | 1982-06-29 | — | — | US | disclosed |
| US-4311610-A | Liquid crystalline 5-alkyl-2 (4-acyloxy-phenyl)-pyrimidine | VEB WERK FUR FERNSEHELEKTRONIK IM VEB KOMBINAT MIKROELEKTRONIK (DD) | 1982-01-19 | — | — | US | disclosed |
| US-4285932-A | Enzyme derivatives for use in the treatment of venous thrombosis | BEECHAM GROUP LIMITED (GB) | 1981-08-25 | — | — | US | disclosed |
| EP-0025119-A1 | Nematic crystalline-liquid 5-alkyl-2-(4-acyloxyphenyl)-pyrimidines for opto-electronic arrangements and process for their preparation | VEB Werk Für Fernsehelektronik im VEB Kombinat Mikroelektronik (DD) | 1981-03-18 | — | — | EP | disclosed |