SCHEMBL1928704

SCHEMBL1928704

CCC(=O)OC(=O)C(C)OC

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.35
ALDH1A1 P00352 4/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
SOAT1 P35610 1/20 0.33
CYP1A2 P05177 1/20 0.32
HPGD P15428 1/20 0.32
CYP2C19 P33261 1/20 0.32
BLM P54132 1/20 0.32
WRN Q14191 1/20 0.32
HIF1A Q16665 1/20 0.32
TRPA1 O75762 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7249667 0.82 SMN1; SMN2 (0.36) ALDH1A1TSHRSMN1; SMN2
SCHEMBL29048961 0.82 SMN1; SMN2 (0.36) ALDH1A1TSHRSMN1; SMN2
SCHEMBL1928703 0.82 SMN1; SMN2 (0.36) ALDH1A1TSHRSMN1; SMN2
SCHEMBL12505873 0.80 MAPT (0.32) MAPT
SCHEMBL25475485 0.79 MGAM (0.37) NAAAALDH1A1MGAMGAASI
SCHEMBL8706762 0.77 TSHR (0.42) NAAAALDH1A1MGAMGAASI
SCHEMBL386957 0.77 NAAA (0.39) NAAAALDH1A1MGAMGAASI
SCHEMBL16640289 0.77 NAAA (0.31) NAAA
SCHEMBL7243118 0.76 NAAA (0.32) NAAAALDH1A1MGAMGAASI
SCHEMBL195331 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115518156-B Nanocomposite capable of releasing near-infrared thermic agent in response manner, preparation method and application 西安交通大学医学院第二附属医院 2023-10-10 CN claimed
CN-109293926-B Protease responsive linear-dendritic block copolymer and preparation method and application thereof 云南师范大学 2021-04-23 CN claimed
CN-110628035-A Enzyme and pH dual-responsive copolymer and preparation method and application thereof 云南师范大学 2019-12-31 CN claimed
CN-1223583-C Peroxyester preparation method ATOFINA (FR) 2005-10-19 CN claimed
CN-1491210-A Process for preparing peroxyesters ���з��ɹ�˾ 2004-04-21 CN claimed
CN-117642410-A Ester derivatives of N4-hydroxycytidine and uses thereof 苏州春海生物医药有限公司 2024-03-01 CN disclosed
CN-115518156-B Nanocomposite capable of releasing near-infrared thermic agent in response manner, preparation method and application 西安交通大学医学院第二附属医院 2023-10-10 CN disclosed
CN-116583530-A N 4 Ester derivatives of hydroxycytidine and their use 苏州春海生物医药有限公司 2023-08-11 CN disclosed
CN-115518156-A Nano compound for responsively releasing near-infrared photothermal agent, preparation method and application 西安交通大学医学院第二附属医院 2022-12-27 CN disclosed
WO-2022262845-A1 ESTER DERIVATIVES OF N4-HYDROXYCYTIDINE AND USE THEREOF SUZHOU SPRING-SEA BIO-PHARMACEUTICALS CO., LTD. (CN) 2022-12-22 WO disclosed
CN-113474008-A NRTI therapy 利物浦大学 2021-10-01 CN disclosed
CN-109293926-B Protease responsive linear-dendritic block copolymer and preparation method and application thereof 云南师范大学 2021-04-23 CN disclosed
EP-1809280-A2 MITOTIC KINESIN INHIBITORS AND METHODS OF USE THEREOF Array Biopharma, Inc. (US) 2007-07-25 EP disclosed
US-20060100161-A1 Antiproliferative agents; anticancer agents; autoimmune disease; antiarthritic agents; graft versus host disease; inflammatory bowel disorders ARRAY BIOPHARMA INC. 2006-05-11 US disclosed
WO-2006044825-A2 MITOTIC KINESIN INHIBITORS AND METHODS OF USE THEREOF ARRAY BIOPHARMA INC. (US) 2006-04-27 WO disclosed
CN-1223583-C Peroxyester preparation method ATOFINA (FR) 2005-10-19 CN disclosed
CN-1491210-A Process for preparing peroxyesters ���з��ɹ�˾ 2004-04-21 CN disclosed
US-6632958-B1 An alkene (1) is added to cyclopentenone (2) under the action of an alkyl lithium and an organic copper reagent to form an adduct, said adduct is reacted with e.g. a carboxylic anhydride (4) to obtain a prostaglandin derivative, which is MITSUBISHI PHARMA CORPORATION (JP) 2003-10-14 US disclosed
EP-1085012-A1 PROCESS FOR PRODUCING PURIFIED PROSTAGLANDIN DERIVATIVE Asahi Glass Co., Ltd. (JP) 2001-03-21 EP disclosed
EP-0447553-B1 BLEACHING COMPOSITION KAO CORP (JP) 1996-06-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060100161-A1 Antiproliferative agents; anticancer agents; autoimmune disease; antiarthritic agents; graft versus host disease; inflammatory bowel disorders KIF5B, KIF2C, KIFC1 NAAA 3664/4885ALDH1A1 1990/4885MGAM 3872/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.