Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | EED | O75530 | 1/20 | 0.41 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.41 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.41 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.41 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3685040 | 0.89 | GPR119 (0.49) | GPR119KDM4EMAPTTHRBEED | |
| SCHEMBL1433174 | 0.87 | GPR119 (0.48) | GPR119KDM4EMAPTTHRBEED | |
| SCHEMBL31016 | 0.87 | GPR119 (0.48) | GPR119KDM4EMAPTTHRBEED | |
| SCHEMBL31017 | 0.87 | GPR119 (0.48) | GPR119KDM4EMAPTTHRBEED | |
| SCHEMBL3710634 | 0.87 | GPR119 (0.48) | GPR119KDM4EMAPTTHRBEED | |
| SCHEMBL17541701 | 0.84 | GPR119 (0.52) | GPR119KDM4EMAPTTHRBEED | |
| SCHEMBL22262887 | 0.83 | GPR119 (0.52) | GPR119KDM4EMAPTTHRBEED | |
| SCHEMBL14359823 | 0.83 | GPR119 (0.52) | GPR119KDM4EMAPTTHRBEED | |
| SCHEMBL15717924 | 0.82 | BAZ2A (0.44) | KDM4E | |
| SCHEMBL419123 | 0.82 | GPR119 (0.51) | GPR119KDM4EMAPTTHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761403-B | 1- (4- (4- (5-Phenyl-4, 5-dihydro-isoxazol-3-yl) thiazol-2-yl) piperidin-1-yl) -ethan-1-one derivatives and related compounds as crop protection fungicides | PI工业有限公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-115052875-B | 4- (4, 5-Dihydroisoxazol-3-yl) thiazol-2-yl) piperidine-thioimine or sulphoxide-imine derivatives and related compounds as fungicides for crop protection | PI工业有限公司 | 2024-07-12 | — | — | CN | disclosed |
| EP-2670747-B1 | HETEROARYL PIPERIDINE AND HETEROARYL PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2023-07-19 | — | — | EP | disclosed |
| EP-4058450-A2 | 4-(4-(4,5-DIHYDROISOXAZOL-3-YL)THIAZOL-2-YL) PIPERIDINE SULFILIMINE AND SULFOXIMINE DERIVATIVES AND RELATED COMPOUNDS AS FUNGICIDES FOR CROP PROTECTION | PI Industries Ltd. (IN) | 2022-09-21 | — | — | EP | disclosed |
| CN-115052875-A | 4- (4- (4, 5-dihydroisoxazol-3-yl) thiazol-2-yl) piperidinethimine or sulfoximine derivatives as fungicides for crop protection and related compounds | PI工业有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-114761403-A | 1- (4- (4- (5-phenyl-4, 5-dihydroisoxazol-3-yl) thiazol-2-yl) piperidin-1-yl) -ethan-1-one derivatives and related compounds as crop protection fungicides | PI工业有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114702411-A | Method for producing 1, 2-benzenedimethanol compound | 高文作物保护公司 | 2022-07-05 | — | — | CN | disclosed |
| WO-2022130188-A1 | AGROCHEMICAL COMPOSITION COMPRISING PIPERIDINE THIAZOLE COMPOUNDS | PI INDUSTRIES LTD. (IN) | 2022-06-23 | — | — | WO | disclosed |
| CN-108602765-B | Method for producing 1, 2-benzenedimethanol compound | 高文有限公司 | 2022-05-03 | — | — | CN | disclosed |
| US-11274076-B2 | Process for preparing 1, 2-benzenedimethanol compound | GOWAN COMPANY, L.L.C. (US) | 2022-03-15 | — | — | US | disclosed |
| EP-2111107-A2 | HETEROCYCLIC RECEPTOR AGONISTS FOR THE TREATMENT OF DIABETES AND METABOLIC DISORDERS | Metabolex Inc. (US) | 2009-10-28 | — | — | EP | disclosed |
| WO-2009123992-A1 | OXYMETHYLENE ARYL COMPOUNDS AND USES THEREOF | METABOLEX, INC. (US) | 2009-10-08 | — | — | WO | disclosed |
| WO-2009094445-A2 | FUNGICIDAL HETERCYCLIC COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-30 | — | — | WO | disclosed |
| US-20090156592-A1 | Fungicidal Azocyclic Amides | E.I. DU PONT DE NEMOURS AND COMPANY (DE) | 2009-06-18 | — | — | US | disclosed |
| WO-2009055514-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-04-30 | — | — | WO | disclosed |
| EP-2049111-A2 | FUNGICIDAL AZOCYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-04-22 | — | — | EP | disclosed |
| US-20090054475-A1 | treatment of Type II diabetes and other diseases associated with poor glycemic control | METABOLEX, INC. (US) | 2009-02-26 | — | — | US | disclosed |
| WO-2008083238-A2 | HETEROCYCLIC RECEPTOR AGONISTS FOR THE TREATMENT OF DIABETES AND METABOLIC DISORDERS | METABOLEX INC. (US) | 2008-07-10 | — | — | WO | disclosed |
| WO-2008013925-A2 | FUNGICIDAL AZOCYCLIC AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-01-31 | — | — | WO | disclosed |
| WO-2008013622-A2 | FUNGICIDAL AZOCYCLIC AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156592-A1 | Fungicidal Azocyclic Amides | ARG1, NAT1, CHRM1 | GPR119 888/4885KDM4E 1248/4885MAPT 4131/4885 |
| US-20090054475-A1 | treatment of Type II diabetes and other diseases associated with poor glycemic control | SLC5A2, IAPP, GPR119 | GPR119 3/4885KDM4E 2876/4885MAPT 3785/4885 |
| US-11274076-B2 | Process for preparing 1, 2-benzenedimethanol compound | ADH1A, ADH1C, CYP2E1 | GPR119 4543/4885KDM4E 3316/4885MAPT 3757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.