Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | EED | O75530 | 1/20 | 0.39 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.39 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.39 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.39 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3710634 | 1.00 | GPR119 (0.48) | GPR119KDM4EMAPTTHRBEED | |
| SCHEMBL31016 | 1.00 | GPR119 (0.48) | GPR119KDM4EMAPTTHRBEED | |
| SCHEMBL192925 | 0.87 | GPR119 (0.50) | GPR119KDM4EMAPTTHRBEED | |
| SCHEMBL3685040 | 0.86 | GPR119 (0.49) | GPR119KDM4EMAPTTHRBEED | |
| SCHEMBL1433174 | 0.84 | GPR119 (0.48) | GPR119KDM4EMAPTTHRBEED | |
| SCHEMBL15717199 | 0.83 | BAZ2A (0.40) | KDM4E | |
| SCHEMBL15717197 | 0.83 | BAZ2A (0.40) | KDM4E | |
| SCHEMBL2454658 | 0.82 | FAAH (0.38) | HTT | |
| SCHEMBL15718159 | 0.82 | FAAH (0.38) | HTT | |
| SCHEMBL2454657 | 0.82 | FAAH (0.38) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761403-B | 1- (4- (4- (5-Phenyl-4, 5-dihydro-isoxazol-3-yl) thiazol-2-yl) piperidin-1-yl) -ethan-1-one derivatives and related compounds as crop protection fungicides | PI工业有限公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-115052875-B | 4- (4, 5-Dihydroisoxazol-3-yl) thiazol-2-yl) piperidine-thioimine or sulphoxide-imine derivatives and related compounds as fungicides for crop protection | PI工业有限公司 | 2024-07-12 | — | — | CN | disclosed |
| EP-2670747-B1 | HETEROARYL PIPERIDINE AND HETEROARYL PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2023-07-19 | — | — | EP | disclosed |
| CN-115052875-A | 4- (4- (4, 5-dihydroisoxazol-3-yl) thiazol-2-yl) piperidinethimine or sulfoximine derivatives as fungicides for crop protection and related compounds | PI工业有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-114761403-A | 1- (4- (4- (5-phenyl-4, 5-dihydroisoxazol-3-yl) thiazol-2-yl) piperidin-1-yl) -ethan-1-one derivatives and related compounds as crop protection fungicides | PI工业有限公司 | 2022-07-15 | — | — | CN | disclosed |
| EP-3241829-B1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2020-12-23 | — | — | EP | disclosed |
| CN-111655687-A | Novel fungicidal heterocyclic compounds | PI工业有限公司 | 2020-09-11 | — | — | CN | disclosed |
| EP-2603508-B1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2019-03-13 | — | — | EP | disclosed |
| US-10004232-B2 | Piperidine pyrazoles as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2018-06-26 | — | — | US | disclosed |
| EP-2609094-B1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER IP GMBH (DE) | 2018-05-30 | — | — | EP | disclosed |
| CN-102781937-A | Bis(difluormethyl)pyrazoles used as fungicides | BAYER CROPSCIENCE AG | 2012-11-14 | — | — | CN | disclosed |
| EP-2516426-A1 | BIS(DIFLUORMETHYL)PYRAZOLES USED AS FUNGICIDES | Bayer CropScience AG (DE) | 2012-10-31 | — | — | EP | disclosed |
| US-20120245204-A1 | Unknown | BAYER CROPSCIENCE AG (DE) | 2012-09-27 | — | — | US | disclosed |
| US-20120122928-A1 | Heteroarylpiperidine and -Piperazine Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2012-05-17 | — | — | US | disclosed |
| US-20120122929-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2012-05-17 | — | — | US | disclosed |
| WO-2012025557-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2012-03-01 | — | — | WO | disclosed |
| EP-2423210-A1 | Heteroarylpiperidine and heteroarylpiperazine derivatives as fungicides | Bayer CropScience AG (DE) | 2012-02-29 | — | — | EP | disclosed |
| WO-2012020060-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2012-02-16 | — | — | WO | disclosed |
| US-20110224257-A1 | Bis(difluoromethyl)pyrazoles as Fungicides | BAYER CROPSCIENCE AG (DE) | 2011-09-15 | — | — | US | disclosed |
| WO-2011076699-A1 | BIS(DIFLUORMETHYL)PYRAZOLES USED AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122929-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | CYP1A1, PRXL2A, CYP1A2 | GPR119 2415/4885KDM4E 1830/4885MAPT 3865/4885 |
| US-10004232-B2 | Piperidine pyrazoles as fungicides | CAT, PIR, CYP51A1 | GPR119 2529/4885KDM4E 1914/4885MAPT 3443/4885 |
| US-20110224257-A1 | Bis(difluoromethyl)pyrazoles as Fungicides | CYP1A1, CYP4X1, CYP2F1 | GPR119 2184/4885KDM4E 2370/4885MAPT 2249/4885 |
| US-20120245204-A1 | Unknown | CYP4Z1, DPM1, ERG28 | GPR119 3763/4885KDM4E 2169/4885MAPT 2379/4885 |
| US-20120122928-A1 | Heteroarylpiperidine and -Piperazine Derivatives as Fungicides | CYP1A1, PRXL2A, CYP1A2 | GPR119 2499/4885KDM4E 1773/4885MAPT 3860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.