Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | HPGD | P15428 | 3/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25527364 | 0.85 | ALDH1A1 (0.67) | KDM4EALDH1A1HPGDHSD17B10CYP2C19 | |
| SCHEMBL1996213 | 0.85 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDHSD17B10CYP2C19 | |
| SCHEMBL5940761 | 0.84 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10CYP2C19 | |
| Triflusal SCHEMBL29435450 | 0.83 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10CYP2C19 | |
| Triflusal SCHEMBL29435449 | 0.83 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10CYP2C19 | |
| Triflusal SCHEMBL136423 | 0.83 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10CYP2C19 | |
| SCHEMBL5943428 | 0.82 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10CYP2C19 | |
| SCHEMBL954464 | 0.82 | HSD17B10 (0.66) | KDM4EALDH1A1HPGDHSD17B10CYP2C19 | |
| Triflusal SCHEMBL4960641 | 0.82 | KDM4E (0.97) | KDM4EALDH1A1HPGDHSD17B10CYP2C19 | |
| SCHEMBL4307017 | 0.81 | KDM4E (0.78) | KDM4EALDH1A1HPGDHSD17B10CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170246193-A1 | FATTY ACID ACETYLATED SALICYLATES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. | 2017-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170246193-A1 | FATTY ACID ACETYLATED SALICYLATES AND THEIR USES | FASN, ACACA, FABP4 | KDM4E 2493/4885ALDH1A1 285/4885HPGD 510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.