SCHEMBL19294249

SCHEMBL19294249

Cc1ccc(Oc2ccc(Cl)cc2O)c(O)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 5/20 0.67
NR1I2 O75469 1/20 0.67
LMNA P02545 1/20 0.67
PGR P06401 1/20 0.67
HSP90AA1 P07900 1/20 0.67
ADORA3 P0DMS8 1/20 0.67
MAPT P10636 1/20 0.67
HSPA5 P11021 1/20 0.67
HPGD P15428 1/20 0.67
CBR1 P16152 1/20 0.67
TBXA2R P21731 1/20 0.67
SLC6A2 P23975 1/20 0.67
AGTR1 P30556 1/20 0.67
SLC6A3 Q01959 1/20 0.67
KCNMA1 Q12791 1/20 0.46
TRPA1 O75762 1/20 0.45
ALDH1A1 P00352 1/20 0.43
CYP3A4 P08684 1/20 0.43
TSHR P16473 1/20 0.43
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12286177 0.91 TTR (0.77) TTRNR1I2LMNAPGRHSP90AA1
SCHEMBL9908124 0.91 TTR (0.77) TTRNR1I2LMNAPGRHSP90AA1
SCHEMBL10540653 0.88 TTR (0.83) TTRNR1I2LMNAPGRHSP90AA1
SCHEMBL10292484 0.88 TRPA1 (0.56) TTRNR1I2LMNAPGRHSP90AA1
SCHEMBL13778174 0.85 TTR (0.58) TTRNR1I2LMNAPGRHSP90AA1
SCHEMBL12386586 0.85 AR (0.49) TTRNR1I2LMNAPGRHSP90AA1
SCHEMBL15242475 0.85 SLC6A2 (0.67) TTRNR1I2LMNAPGRHSP90AA1
SCHEMBL19843836 0.85 TTR (0.61) TTRNR1I2LMNAPGRHSP90AA1
SCHEMBL15242472 0.84 TTR (0.57) TTRNR1I2LMNAPGRHSP90AA1
Triclosan SCHEMBL7623180 0.83 TTR (0.63) TTRNR1I2LMNAPGRHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9901100-B2 Low pH disinfectant composition MEDIVATORS INC. (US) 2018-02-27 US disclosed
US-20170245502-A1 LOW pH DISINFECTANT COMPOSITION MEDIVATORS INC. 2017-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170245502-A1 LOW pH DISINFECTANT COMPOSITION ADH1C, ADH1A, ADH5 TTR 3888/4885NR1I2 4263/4885LMNA 2816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.