SCHEMBL9908124

SCHEMBL9908124

Cc1ccc(Oc2ccc(Cl)cc2O)c(Cl)c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 6/20 0.77
NR1I2 O75469 1/20 0.77
LMNA P02545 1/20 0.77
PGR P06401 1/20 0.77
HSP90AA1 P07900 1/20 0.77
ADORA3 P0DMS8 1/20 0.77
MAPT P10636 1/20 0.77
HSPA5 P11021 1/20 0.77
HPGD P15428 1/20 0.77
CBR1 P16152 1/20 0.77
TBXA2R P21731 1/20 0.77
SLC6A2 P23975 1/20 0.77
AGTR1 P30556 1/20 0.77
SLC6A3 Q01959 1/20 0.77
ALDH1A1 P00352 1/20 0.44
CYP3A4 P08684 1/20 0.44
TSHR P16473 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
KCNMA1 Q12791 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12286177 0.93 TTR (0.77) TTRNR1I2LMNAPGRHSP90AA1
SCHEMBL19294249 0.91 TTR (0.67) TTRNR1I2LMNAPGRHSP90AA1
SCHEMBL19843836 0.91 TTR (0.61) TTRNR1I2LMNAPGRHSP90AA1
Triclosan SCHEMBL28283932 0.87 TTR (0.92) TTRNR1I2LMNAPGRHSP90AA1
Triclosan SCHEMBL526378 0.87 TTR (1.00) TTRNR1I2LMNAPGRHSP90AA1
Triclosan SCHEMBL29356111 0.87 TTR (1.00) TTRNR1I2LMNAPGRHSP90AA1
Triclosan SCHEMBL29354475 0.87 TTR (1.00) TTRNR1I2LMNAPGRHSP90AA1
Triclosan SCHEMBL3269 0.87 TTR (1.00) TTRNR1I2LMNAPGRHSP90AA1
Triclosan SCHEMBL29367506 0.87 TTR (1.00) TTRNR1I2LMNAPGRHSP90AA1
Triclosan SCHEMBL8975439 0.85 TTR (0.96) TTRNR1I2LMNAPGRHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11666050-B2 Enhancing the antimicrobial activity of biocides with polymers BASF SE (DE) 2023-06-06 US disclosed
US-11647746-B2 Enhancing the antimicrobial activity of biocides with polymers BASF SE (DE) 2023-05-16 US disclosed
US-9757407-B2 Treatment of viral infections by modulation of host cell metabolic pathways THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2017-09-12 US disclosed
US-20160346309-A1 TREATMENT OF VIRAL INFECTIONS BY MODULATION OF HOST CELL METABOLIC PATHWAYS UNIV PRINCETON (US) 2016-12-01 US disclosed
US-20150182436-A1 DEODORANT COMPOSITIONS HAVING ANTIBACTERIAL AND ODOR BLOCKING PROPERTIES AND METHODS FOR USING THE SAME THE DIAL CORPORATION 2015-07-02 US disclosed
US-20150139949-A1 ANTI-VIRAL COMBINATION THERAPY KOYUNCU EMRE (US) 2015-05-21 US disclosed
US-9029413-B2 Treatment of viral infections by modulation of host cell metabolic pathways THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2015-05-12 US disclosed
US-20140369953-A1 Enhancing the Antimicrobial Activity of Biocides with Polymers BASF SE (DE) 2014-12-18 US disclosed
US-20130065850-A1 TREATMENT OF VIRAL INFECTIONS BY MODULATION OF HOST CELL METABOLIC PATHWAYS THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2013-03-14 US disclosed
US-20120276219-A1 COMPOSITIONS HAVING A HIGH ANTIVIRAL AND ANTIBACTERIAL EFFICACY THE DIAL CORPORATION (US) 2012-11-01 US disclosed
US-20120141600-A1 Compositions Having a High Antiviral and Antibacterial Efficacy THE DIAL CORPORATION (US) 2012-06-07 US disclosed
US-7795196-B2 Hand-washing method utilizing antimicrobial liquid hand soap compositions with tactile signal GEORGIA-PACIFIC CONSUMER PRODUCTS LP (US) 2010-09-14 US disclosed
US-20090175761-A1 Hand-washing method utilizing antimicrobial liquid hand soap compositions with tactile signal GPCP IP HOLDINGS LLC 2009-07-09 US disclosed
US-7521404-B2 Antimicrobial liquid hand soap composition with tactile signal comprising a phospholipid surfactant GEORGIA-PACIFIC CONSUMER PRODUCTS LP (US) 2009-04-21 US disclosed
WO-2007142967-A2 ALCOHOL-CONTAINING ANTIMICROBIAL COMPOSITIONS HAVING IMPROVED EFFICACY THE DIAL CORPORATION (US) 2007-12-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11647746-B2 Enhancing the antimicrobial activity of biocides with polymers CAT, AOC1, DDT TTR 4735/4885NR1I2 4422/4885LMNA 4556/4885
US-20120276219-A1 COMPOSITIONS HAVING A HIGH ANTIVIRAL AND ANTIBACTERIAL EFFICACY ZC3HAV1, ZC3HAV1L, ZFR TTR 2062/4885NR1I2 3136/4885LMNA 4166/4885
US-20160346309-A1 TREATMENT OF VIRAL INFECTIONS BY MODULATION OF HOST CELL METABOLIC PATHWAYS GOT2, MAVS, ME3 TTR 4184/4885NR1I2 2008/4885LMNA 4191/4885
US-20140369953-A1 Enhancing the Antimicrobial Activity of Biocides with Polymers CAT, AOC1, DDT TTR 4735/4885NR1I2 4422/4885LMNA 4556/4885
US-20150182436-A1 DEODORANT COMPOSITIONS HAVING ANTIBACTERIAL AND ODOR BLOCKING PROPERTIES AND METHODS FOR USING THE SAME LPO, TYR, DDO TTR 1766/4885NR1I2 3702/4885LMNA 4617/4885
US-11666050-B2 Enhancing the antimicrobial activity of biocides with polymers CAT, AOC1, DDT TTR 4735/4885NR1I2 4422/4885LMNA 4556/4885
US-20130065850-A1 TREATMENT OF VIRAL INFECTIONS BY MODULATION OF HOST CELL METABOLIC PATHWAYS GOT2, MAVS, ME3 TTR 4184/4885NR1I2 2008/4885LMNA 4191/4885
US-20120141600-A1 Compositions Having a High Antiviral and Antibacterial Efficacy ZC3HAV1, ZC3HAV1L, ZFR TTR 2062/4885NR1I2 3136/4885LMNA 4166/4885
US-20150139949-A1 ANTI-VIRAL COMBINATION THERAPY HAVCR2, MAVS, ZC3HAV1 TTR 4465/4885NR1I2 2064/4885LMNA 4540/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.