SCHEMBL1929979

SCHEMBL1929979

O=C(CO)Nc1ccc(OC(=O)CO)cc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.50
KMT2A Q03164 4/20 0.49
MEN1 O00255 2/20 0.49
HTT P42858 5/20 0.47
ALDH1A1 P00352 3/20 0.47
POLB P06746 1/20 0.47
LMNA P02545 3/20 0.47
RAB9A P51151 2/20 0.47
OPRK1 P41145 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
KLK7 P49862 1/20 0.45
MAPT P10636 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
HSD17B10 Q99714 2/20 0.44
RNF4 P78317 1/20 0.44
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1930736 0.84 KMT2A (0.70) KMT2AMEN1HTTALDH1A1LMNA
SCHEMBL1931453 0.82 KMT2A (0.54) GAAKMT2AMEN1HTTALDH1A1
SCHEMBL2352584 0.82 MEN1 (0.56) GAAKMT2AMEN1HTTALDH1A1
SCHEMBL2089593 0.79 L3MBTL1 (0.71) KMT2AMEN1HTTALDH1A1LMNA
SCHEMBL10713248 0.76 RAB9A (0.63) GAAKMT2AMEN1HTTALDH1A1
SCHEMBL10801122 0.76 POLB (0.54) GAAKMT2AMEN1HTTALDH1A1
Fenacetinol SCHEMBL2850567 0.76 POLB (0.80) KMT2AMEN1HTTALDH1A1POLB
SCHEMBL829250 0.76 MEN1 (0.62) KMT2AMEN1HTTALDH1A1POLB
SCHEMBL19609973 0.75 MAPT (0.56) GAAKMT2AMEN1HTTALDH1A1
SCHEMBL2092934 0.75 EPHX2 (0.69) KMT2AMEN1ALDH1A1POLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE45548-E1 Functionalized drugs and polymers derived therefrom BEZWADA BIOMEDICAL, LLC (US) 2015-06-09 US disclosed
US-RE45548-E1 Functionalized drugs and polymers derived therefrom BEZWADA BIOMEDICAL, LLC (US) 2015-06-09 US disclosed
US-8409559-B2 Functionalized drugs and polymers derived therefrom Bezwada Biomedical, Inc. (US) 2013-04-02 US disclosed
US-8409559-B2 Functionalized drugs and polymers derived therefrom Bezwada Biomedical, Inc. (US) 2013-04-02 US disclosed
US-8372882-B2 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-02-12 US disclosed
US-8372882-B2 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-02-12 US disclosed
US-8372882-B2 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-02-12 US disclosed
US-20110130448-A1 FUNCTIONALIZED PHENOLIC ESTERS AND AMIDES AND POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2011-06-02 US disclosed
US-20110130448-A1 FUNCTIONALIZED PHENOLIC ESTERS AND AMIDES AND POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2011-06-02 US disclosed
US-20110130448-A1 FUNCTIONALIZED PHENOLIC ESTERS AND AMIDES AND POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2011-06-02 US disclosed
US-7858077-B2 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL LLC (US) 2010-12-28 US disclosed
US-7858077-B2 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL LLC (US) 2010-12-28 US disclosed
US-7858077-B2 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL LLC (US) 2010-12-28 US disclosed
US-20100152272-A1 FUNCTIONALIZED DRUGS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2010-06-17 US disclosed
US-20100152272-A1 FUNCTIONALIZED DRUGS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2010-06-17 US disclosed
US-7691364-B2 Functionalized drugs and polymers derived therefrom BEZWADA BIOMEDICAL, LLC (US) 2010-04-06 US disclosed
US-7691364-B2 Functionalized drugs and polymers derived therefrom BEZWADA BIOMEDICAL, LLC (US) 2010-04-06 US disclosed
WO-2007030538-A2 FUNCTIONALIZED DRUGS AND POLYMERS DERIVED THEREFROM BEZWADA BIOMEDICAL LLC (US) 2007-03-15 WO disclosed
US-20060173065-A1 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL LLC 2006-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100152272-A1 FUNCTIONALIZED DRUGS AND POLYMERS THEREFROM OGFR, LOX, DDO GAA 876/4885KMT2A 3366/4885MEN1 3970/4885
US-20060173065-A1 Functionalized phenolic esters and amides and polymers therefrom HAAO, HAO2, HCAR3 GAA 874/4885KMT2A 2066/4885MEN1 4878/4885
US-20110130448-A1 FUNCTIONALIZED PHENOLIC ESTERS AND AMIDES AND POLYMERS THEREFROM HAO2, HCAR2, HAAO GAA 958/4885KMT2A 1798/4885MEN1 4874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.