Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | SDHB | P21912 | 1/20 | 0.32 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19299835 | 0.93 | LMNA (0.32) | LMNATP53MAPTKDM4EALDH1A1 | |
| SCHEMBL19299812 | 0.90 | PTGS2 (0.35) | LMNATP53MAPTKDM4EALDH1A1 | |
| SCHEMBL21948999 | 0.85 | — | — | |
| SCHEMBL18072957 | 0.84 | POLB (0.41) | LMNATP53MAPTKDM4EALDH1A1 | |
| SCHEMBL19299809 | 0.84 | RORC (0.34) | LMNATP53MAPTKDM4EALDH1A1 | |
| SCHEMBL21948584 | 0.80 | — | — | |
| SCHEMBL18819869 | 0.79 | PTGS2 (0.36) | MAPTACSS2PTGS2PTGS1 | |
| SCHEMBL18173807 | 0.78 | SDHB (0.32) | SDHB | |
| SCHEMBL20549754 | 0.77 | TP53 (0.34) | LMNATP53MAPTKDM4EALDH1A1 | |
| SCHEMBL18072962 | 0.74 | POLB (0.41) | KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017144341-A1 | CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-08-31 | — | — | WO | disclosed |