Pectolinarigenin

Pectolinarigenin

SCHEMBL243686

COc1ccc(-c2cc(=O)c3c(O)c(OC)c(O)cc3o2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 1.00
FLT3 P36888 5/20 1.00
MEN1 O00255 5/20 1.00
KMT2A Q03164 5/20 1.00
NPC1 O15118 4/20 1.00
POLB P06746 4/20 1.00
RAB9A P51151 3/20 1.00
KIT P10721 1/20 1.00
NFKB1 P19838 1/20 1.00
OPRD1 P41143 1/20 1.00
NFKB2 Q00653 1/20 1.00
RELA Q04206 1/20 1.00
GFER P55789 2/20 0.83
TDP1 Q9NUW8 2/20 0.83
GABRP O00591 1/20 0.83
GABRD O14764 1/20 0.83
PIM1 P11309 1/20 0.83
GABRA1 P14867 1/20 0.83
GABRB1 P18505 1/20 0.83
GABRG2 P18507 1/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pectolinarigenin SCHEMBL29606971 1.00 MAPT (1.00) MAPTFLT3MEN1KMT2ANPC1
SCHEMBL8063178 0.91 FLT3 (0.83) MAPTFLT3MEN1KMT2ANPC1
Hispidulin SCHEMBL29458970 0.91 POLB (1.00) MAPTFLT3MEN1KMT2ANPC1
Hispidulin SCHEMBL514926 0.91 POLB (1.00) MAPTFLT3MEN1KMT2ANPC1
SCHEMBL28732976 0.90 FLT3 (0.81) MAPTFLT3MEN1KMT2ANPC1
SCHEMBL29504103 0.90 FLT3 (0.81) MAPTFLT3MEN1KMT2ANPC1
SCHEMBL6242511 0.90 KMT2A (0.81) MAPTFLT3MEN1KMT2ANPC1
SCHEMBL737628 0.89 FLT3 (0.81) MAPTFLT3MEN1KMT2ANPC1
SCHEMBL17258304 0.89 FLT3 (0.81) MAPTFLT3MEN1KMT2ANPC1
Salvigenin SCHEMBL1427018 0.89 FLT3 (1.00) MAPTFLT3MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 441 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709365-A2 FORMULATIONS OF PECTOLINARIGENIN Debut Biotechnology, Inc. (US) 2026-03-18 EP claimed
EP-4698662-A2 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES AskBio Inc. (US) 2026-02-25 EP claimed
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 EP claimed
WO-2024220449-A9 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES AskBio Inc. (US) 2025-04-03 WO claimed
US-20250011393-A1 FLAVONOID-COLLAGEN CROSSLINKED ANTIOXIDANT HYDROGEL NORTH CAROLINA STATE UNIVERSITY 2025-01-09 US claimed
WO-2024258363-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES SAHIN FIKRET (TR) 2024-12-19 WO claimed
WO-2024233739-A2 FORMULATIONS OF PECTOLINARIGENIN Debut Biotechnology, Inc. (US) 2024-11-14 WO claimed
WO-2024220449-A2 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES ASKLEPIOS BIOPHARMACEUTICAL, INC. (US) 2024-10-24 WO claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
US-20240016777-A1 COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS BETH ISRAEL DEACONESS MEDICAL CENTER, INC. 2024-01-18 US claimed
WO-2003051287-A2 TOPICAL COMPOSITIONS AND METHODS FOR TREATMENT OF ADVERSE EFFECTS OF IONIZING RADIATION THE QUIGLEY CORPORATION (US) 2003-06-26 WO claimed
US-20030118536-A1 Topical compositions and methods for treatment of adverse effects of ionizing radiation QUIGLEY CORPORATION, THE 2003-06-26 US claimed
US-20030105031-A1 Methods for the treatment of skin disorders QUIGLEY CORPORATION, THE 2003-06-05 US claimed
US-20030103954-A1 Oral compositions and methods for prevention, reduction and treatment of radiation injury QUIGLEY CORPORATION, THE 2003-06-05 US claimed
US-20030105027-A1 Nutritional supplements and methods for prevention, reduction and treatment of radiation injury QUIGLEY CORPORATION, THE 2003-06-05 US claimed
WO-2003039452-A2 NUTRITIONAL SUPPLEMENTS AND METHODS FOR PREVENTION, REDUCTION AND TREATMENT OF RADIATION INJURY THE QUIGLEY CORPORATION (US) 2003-05-15 WO claimed
US-6555573-B2 Comprising a cold compounded mixture of a compound that promotes synthesis of nerve growth factor, an aldose reductase inhibitor, antioxidant and carrier; side effect reduction; partial recovery of neurological function in some cases THE QUIGLEY CORPORATION 2003-04-29 US claimed
US-20020165207-A1 Compositions and methods for the treatment of diabetic neuropathy QUIGLEY CORPORATION, THE 2002-11-07 US claimed
US-20020115618-A1 Method and composition for the topical treatment of diabetic neuropathy QUIGLEY CORPORATION, THE 2002-08-22 US claimed
WO-2002049575-A2 METHOD AND COMPOSITION FOR THE TREATMENT OF DIABETIC NEUROPATHY THE QUIGLEY CORPORATION (US) 2002-06-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030103954-A1 Oral compositions and methods for prevention, reduction and treatment of radiation injury FOXO3, BAX, GSTK1 MAPT 4249/4885FLT3 4402/4885MEN1 3382/4885
US-20030105027-A1 Nutritional supplements and methods for prevention, reduction and treatment of radiation injury FOXO3, NQO1, FOXO1 MAPT 3987/4885FLT3 3778/4885MEN1 3289/4885
US-20030105031-A1 Methods for the treatment of skin disorders TYR, CUTA, NFATC1 MAPT 1999/4885FLT3 3965/4885MEN1 4748/4885
US-20240016777-A1 COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS THPO, SERPINB1, SERPINC1 MAPT 2717/4885FLT3 563/4885MEN1 740/4885
US-20030118536-A1 Topical compositions and methods for treatment of adverse effects of ionizing radiation GSTK1, FOXO3, SIK2 MAPT 3237/4885FLT3 3657/4885MEN1 3325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.