Pectolinarigenin

Pectolinarigenin

SCHEMBL29606971

COc1ccc(-c2cc(=O)c3c(O)c(OC)c(O)cc3o2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 1.00
▸ FLT3 P36888 5/20 1.00
▸ MEN1 O00255 5/20 1.00
▸ KMT2A Q03164 5/20 1.00
▸ NPC1 O15118 4/20 1.00
▸ POLB P06746 4/20 1.00
▸ RAB9A P51151 3/20 1.00
▸ KIT P10721 1/20 1.00
▸ NFKB1 P19838 1/20 1.00
▸ OPRD1 P41143 1/20 1.00
▸ NFKB2 Q00653 1/20 1.00
▸ RELA Q04206 1/20 1.00
▸ GFER P55789 2/20 0.83
▸ TDP1 Q9NUW8 2/20 0.83
▸ GABRP O00591 1/20 0.83
▸ GABRD O14764 1/20 0.83
▸ PIM1 P11309 1/20 0.83
▸ GABRA1 P14867 1/20 0.83
▸ GABRB1 P18505 1/20 0.83
▸ GABRG2 P18507 1/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pectolinarigenin SCHEMBL243686 1.00 MAPT (1.00) MAPTFLT3MEN1KMT2ANPC1
SCHEMBL8063178 0.91 FLT3 (0.83) MAPTFLT3MEN1KMT2ANPC1
Hispidulin SCHEMBL514926 0.91 POLB (1.00) MAPTFLT3MEN1KMT2ANPC1
Hispidulin SCHEMBL29458970 0.91 POLB (1.00) MAPTFLT3MEN1KMT2ANPC1
SCHEMBL28732976 0.90 FLT3 (0.81) MAPTFLT3MEN1KMT2ANPC1
SCHEMBL29504103 0.90 FLT3 (0.81) MAPTFLT3MEN1KMT2ANPC1
SCHEMBL6242511 0.90 KMT2A (0.81) MAPTFLT3MEN1KMT2ANPC1
SCHEMBL737628 0.89 FLT3 (0.81) MAPTFLT3MEN1KMT2ANPC1
Salvigenin SCHEMBL1427018 0.89 FLT3 (1.00) MAPTFLT3MEN1KMT2ANPC1
SCHEMBL18601886 0.89 FLT3 (0.80) MAPTFLT3MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4622640-A1 COMPOSITIONS AND METHODS FOR MODULATING SLEEP AND USES THEREOF Brightseed, Inc. (US) 2025-10-01 — — EP claimed
WO-2024112947-A1 COMPOSITIONS AND METHODS FOR MODULATING SLEEP AND USES THEREOF BRIGHTSEED, INC. (US) 2024-05-30 — — WO claimed
US-12590094-B2 Compounds for the treatment of neurodegenerative and metabolic disorders UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2026-03-31 — — US disclosed
EP-4709365-A2 FORMULATIONS OF PECTOLINARIGENIN Debut Biotechnology, Inc. (US) 2026-03-18 — — EP disclosed
EP-4709365-A2 FORMULATIONS OF PECTOLINARIGENIN Debut Biotechnology, Inc. (US) 2026-03-18 — — EP disclosed
EP-4709365-A2 FORMULATIONS OF PECTOLINARIGENIN Debut Biotechnology, Inc. (US) 2026-03-18 — — EP disclosed
EP-4622640-A1 COMPOSITIONS AND METHODS FOR MODULATING SLEEP AND USES THEREOF Brightseed, Inc. (US) 2025-10-01 — — EP disclosed
WO-2025144990-A1 METHODS AND COMPOSITIONS FOR BIOPRODUCTION OF PECTOLINARIGENIN Debut Biotechnology, Inc. (US) 2025-07-03 — — WO disclosed
WO-2024233739-A3 FORMULATIONS OF PECTOLINARIGENIN Debut Biotechnology, Inc. (US) 2025-02-13 — — WO disclosed
WO-2024233739-A3 FORMULATIONS OF PECTOLINARIGENIN Debut Biotechnology, Inc. (US) 2025-02-13 — — WO disclosed
WO-2024233739-A2 FORMULATIONS OF PECTOLINARIGENIN Debut Biotechnology, Inc. (US) 2024-11-14 — — WO disclosed
WO-2024233739-A2 FORMULATIONS OF PECTOLINARIGENIN Debut Biotechnology, Inc. (US) 2024-11-14 — — WO disclosed
WO-2024233739-A2 FORMULATIONS OF PECTOLINARIGENIN Debut Biotechnology, Inc. (US) 2024-11-14 — — WO disclosed
CN-118121650-A Traditional Chinese medicine extract, preparation method thereof and blood component detection method 川北医学院 2024-06-04 — — CN disclosed
WO-2024112947-A1 COMPOSITIONS AND METHODS FOR MODULATING SLEEP AND USES THEREOF BRIGHTSEED, INC. (US) 2024-05-30 — — WO disclosed
WO-2023127826-A1 ELECTROLYTIC CAPACITOR AND LIQUID COMPONENT FOR ELECTROLYTIC CAPACITOR パナソニックIPマネジメント株式会社 2023-07-06 — — WO disclosed
US-20230041523-A1 COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE AND METABOLIC DISORDERS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2023-02-09 — — US disclosed
CN-114432356-A A composition for treating cancer and its preparation method 庞德东 2022-05-06 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590094-B2 Compounds for the treatment of neurodegenerative and metabolic disorders TXN2, SMN1; SMN2, SNCA MAPT 33/4885FLT3 4755/4885MEN1 4241/4885
US-20230041523-A1 COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE AND METABOLIC DISORDERS NLN, GLS, PRNP MAPT 11/4885FLT3 4609/4885MEN1 3772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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