Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | MC5R | P33032 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 8/20 | 0.45 |
| ▸ | PLG | P00747 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 4/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19308226 | 0.84 | PKM (0.52) | USP2LMNATSHRMAPK1HSD17B10 | |
| SCHEMBL12929578 | 0.84 | MC4R (0.47) | MC4RMC5RUSP2LMNATSHR | |
| SCHEMBL19308229 | 0.79 | F2 (0.52) | MC4RMC5RLMNATSHRKMT2A | |
| SCHEMBL19308224 | 0.73 | F2 (0.49) | LMNAKMT2AF2PLGF10 | |
| SCHEMBL12929584 | 0.70 | F2 (0.52) | MC4RMC5RLMNAKMT2AF2 | |
| SCHEMBL8546806 | 0.70 | AKR1C3 (0.51) | LMNATSHRKMT2APKMAKR1C3 | |
| Hydrochloric Acid SCHEMBL5737608 | 0.69 | F10 (0.67) | USP2LMNATSHRMAPK1HSD17B10 | |
| SCHEMBL6787217 | 0.69 | F10 (0.68) | USP2LMNATSHRMAPK1HSD17B10 | |
| SCHEMBL4270641 | 0.68 | CNR1 (0.69) | USP2LMNATSHRMAPK1HSD17B10 | |
| SCHEMBL19308204 | 0.68 | ALDH1A1 (0.51) | LMNAKMT2AF2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9752149-B2 | Matriptase inhibitors and uses thereof against orthomyxoviridae infections | SOCPRA Sciences Sante et Humaines S.E.C. (CA) | 2017-09-05 | — | — | US | disclosed |