Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 10/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | MASP2 | O00187 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL549141 | 0.78 | NQO2 (1.00) | NQO2ALDH1A1TOP1HPGDCASP1 | |
| SCHEMBL13573621 | 0.71 | NQO2 (0.83) | NQO2ALDH1A1TOP1HPGDCASP1 | |
| SCHEMBL13575267 | 0.69 | NQO2 (0.78) | NQO2ALDH1A1TOP1HPGDCASP1 | |
| SCHEMBL6750104 | 0.66 | NQO2 (0.72) | NQO2ALDH1A1TOP1HPGDCASP1 | |
| SCHEMBL27639231 | 0.61 | NQO2 (0.64) | NQO2ALDH1A1TOP1HPGDCASP1 | |
| SCHEMBL394218 | 0.59 | WDR5 (0.80) | NQO2ALDH1A1TOP1HPGDCASP1 | |
| SCHEMBL8973288 | 0.59 | WDR5 (0.80) | NQO2ALDH1A1TOP1HPGDCASP1 | |
| SCHEMBL12348287 | 0.58 | NQO2 (0.59) | NQO2ALDH1A1TOP1HPGDCASP1 | |
| SCHEMBL17345755 | 0.58 | WDR5 (0.41) | NQO2ALDH1A1TOP1HPGDCASP1 | |
| SCHEMBL12348291 | 0.58 | NQO2 (0.58) | NQO2ALDH1A1TOP1HPGDCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9752149-B2 | Matriptase inhibitors and uses thereof against orthomyxoviridae infections | SOCPRA Sciences Sante et Humaines S.E.C. (CA) | 2017-09-05 | — | — | US | disclosed |