Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | PGK2 | P07205 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | TPMT | P51580 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17576038 | 0.86 | RPS6KB1 (0.36) | NR3C1PGRNR3C2RPS6KB1 | |
| SCHEMBL15840092 | 0.77 | SMN1; SMN2 (0.46) | KMT2AGAAHPGDALDH1A1POLB | |
| SCHEMBL18932620 | 0.72 | ALDH1A1 (0.38) | PGK1PGK2GAAIDH1ALDH1A1 | |
| SCHEMBL15218453 | 0.71 | KMT2A (0.47) | KMT2ANR3C1PGRNR3C2ALDH1A1 | |
| SCHEMBL4832407 | 0.70 | KDM4E (0.44) | PGK1PGK2IDH1ALDH1A1TSHR | |
| SCHEMBL465569 | 0.70 | GAA (0.49) | PGK1PGK2KMT2AGAAHPGD | |
| Hydrochloric Acid SCHEMBL5705745 | 0.69 | KDM4E (0.48) | PGK1PGK2IDH1ALDH1A1TSHR | |
| SCHEMBL31276885 | 0.69 | IDO1 (0.44) | PGK1PGK2KMT2AGAAALDH1A1 | |
| SCHEMBL8433070 | 0.69 | CHRM2 (0.45) | KMT2AALDH1A1TSHRMAOA | |
| SCHEMBL27795929 | 0.69 | PGK1 (0.38) | PGK1PGK2KMT2AIDH1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170253569-A1 | THIAZOLIDINONE COMPOUNDS AND USE THEREOF | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2017-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170253569-A1 | THIAZOLIDINONE COMPOUNDS AND USE THEREOF | OPRL1, OPRD1, OPRK1 | PGK1 3241/4885PGK2 2813/4885KMT2A 3536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.