SCHEMBL19320232

SCHEMBL19320232

O=C(CC(=O)CC(F)(F)F)CC(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PLA2G4A P47712 1/20 0.35
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CA2 P00918 1/20 0.32
HTT P42858 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8650339 0.87 TDP1 (0.43) PLA2G4AALDH1A1
SCHEMBL1058273 0.86 PLA2G4A (0.38) PLA2G4AHTT
SCHEMBL4206545 0.85 KDM4E (0.44) PLA2G4AALDH1A1HTT
SCHEMBL5211347 0.85 LDHA (0.42) PLA2G4AALDH1A1
SCHEMBL4976795 0.83 PLOD2 (0.38) PLA2G4AALDH1A1POLBSMN1; SMN2CA2
SCHEMBL31412009 0.83 KDM4E (0.42) PLA2G4AALDH1A1HTT
SCHEMBL19320233 0.83 PLA2G4A (0.43) PLA2G4AMEN1KMT2A
SCHEMBL11983873 0.81 CYP2C19 (0.41) PLA2G4AALDH1A1CA2
SCHEMBL11983876 0.79 PLA2G4A (0.33) PLA2G4A
SCHEMBL12603663 0.79 MGAM (0.44) PLA2G4AALDH1A1HTTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170253623-A1 IRIDIUM COMPLEX PRODUCTION METHOD TANAKA KIKINZOKU KOGYO K.K. (JP) 2017-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170253623-A1 IRIDIUM COMPLEX PRODUCTION METHOD IPMK, TALDO1, BCKDK PLA2G4A 3799/4885ALDH1A1 1033/4885POLB 1086/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.