Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 6/20 | 0.36 |
| ▸ | CES2 | O00748 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 8/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9935031 | 0.88 | PLA2G4A (0.52) | PLA2G4ACES1CES2HDAC3HDAC1 | |
| SCHEMBL19320232 | 0.83 | PLA2G4A (0.35) | PLA2G4AMEN1KMT2A | |
| SCHEMBL8650339 | 0.81 | TDP1 (0.43) | PLA2G4AFFAR3 | |
| SCHEMBL1701664 | 0.80 | CES2 (0.53) | CES1CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL14318586 | 0.79 | HDAC3 (0.42) | CES1CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL3126473 | 0.77 | CES2 (0.50) | CES1CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL5667473 | 0.77 | CES2 (0.50) | CES1CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL11434918 | 0.77 | CES2 (0.50) | CES1CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL29053185 | 0.77 | CES2 (0.50) | CES1CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL28665298 | 0.77 | HAO1 (0.41) | PLA2G4ACES1CES2FAAHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170253623-A1 | IRIDIUM COMPLEX PRODUCTION METHOD | TANAKA KIKINZOKU KOGYO K.K. (JP) | 2017-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170253623-A1 | IRIDIUM COMPLEX PRODUCTION METHOD | IPMK, TALDO1, BCKDK | PLA2G4A 3799/4885CES1 2112/4885CES2 3625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.